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SARS-CoV-2-IN-13

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-144770
    SARS-CoV-2-IN-13

    		SARS-CoV Infection
    SARS-CoV-2-IN-13 (compound 5) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.057 μM. SARS-CoV-2-IN-13 is a niclosamide analogue. SARS-CoV-2-IN-13 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally .
    <em>SARS-CoV-2-IN-13</em>
  • HY-150622
    SARS-CoV-2 nsp13-IN-1

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-1 (compound C1) is a potent nsp13 (non-structural protein 13) inhibitor. SARS-CoV-2 nsp13-IN-1 only inhibits nsp13 ssDNA + ATPase, with an IC50 of 6 μM. SARS-CoV-2 nsp13-IN-1 does not inhibit ssDNA - ATPase. SARS-CoV-2 nsp13-IN-1 can be used for COVID-19 research .
    <em>SARS</em>-CoV-2 nsp13-IN-1
  • HY-150626
    SARS-CoV-2 nsp13-IN-5

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-5 (compound C6) is a potent SARS-CoV-2 nsp13 inhibitor with IC50 values of 50 and 55 μM for ssDNA + ATPase and ssDNA - ATPase. SARS-CoV-2 nsp13-IN-5 can be used for researching anti-COVID-19 .
    <em>SARS</em>-CoV-2 nsp13-IN-5
  • HY-163186
    SARS-CoV-2 Mpro-IN-13

    		SARS-CoV Infection
    SARS-CoV-2 Mpro-IN-13 (compound 20j) is a covalent SARS-CoV-2 Protease Mpro inhibitor with an IC50 value of 19.0 nM. SARS-CoV-2 Mpro-IN-13 processes antiviral activity with an EC50 value of 138.1 nM .
    <em>SARS</em>-CoV-2 Mpro-IN-13
  • HY-146987
    FWM-3

    		SARS-CoV Infection
    FWM-3 is a potent SARS-CoV-2 NSP13 helicase inhibitor .
    FWM-3
  • HY-144799
    FWM-4

    		SARS-CoV Infection
    FWM-4 is a potent SARS-COV-2 NSP13 helicase enzyme inhibitor .
    FWM-4
  • HY-150632
    SARS-CoV-2 nsp13-IN-6

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-6 (compound C5) is a potent SARS-CoV-2 non-structural protein 13 (nsp13) inhibitor with IC50 values of 27 and 33 μM for ssDNA + ATPase and ssDNA - ATPase. SARS-CoV-2 nsp13-IN-6 can be used for researching anti-COVID-19 .
    <em>SARS</em>-CoV-2 nsp13-IN-6
  • HY-150625
    SARS-CoV-2 nsp13-IN-4

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-4 (C4 (d)) is a potent and selective nsp13 helicase small-molecule inhibitor and inhibit the ssDNA+ ATPase activity of nsp13 with an IC50 value of 57 μM. SARS-CoV-2 nsp13-IN-4 is agentlike molecule with molecular weight of less than 450Da and can provide a broad-spectrum antiviral effect .
    <em>SARS</em>-CoV-2 nsp13-IN-4
  • HY-144798
    FWM-5

    		SARS-CoV Infection
    FWM-5 is a potent NSP13 helicase inhibitor. SARS-COV-2 NSP13 helicase enzyme plays crucial role in the virus life cycle. FWM-5 has the potential for the research of infection diseases .
    FWM-5
  • HY-150623
    SARS-CoV-2 nsp13-IN-2

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-2 (Compound C2) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 42 μM against nsp13 ssDNA + ATPase .
    <em>SARS</em>-CoV-2 nsp13-IN-2
  • HY-150624
    SARS-CoV-2 nsp13-IN-3

    		SARS-CoV Infection
    SARS-CoV-2 nsp13-IN-3 (Compound C3) is a SARS-CoV-2 non-structural protein 13 (nsp13) small-molecule inhibitor with an IC50 of 32 μM against nsp13 ssDNA + ATPase .
    <em>SARS</em>-CoV-2 nsp13-IN-3
  • HY-144800
    FWM-1

    		SARS-CoV Infection
    FWM-1 is a potent SARS-COV-2 NSP13 helicase enzyme inhibitor with binding free energy equals -328.6 kcal/mol. FWM-1 effectively disrupts the binding of ATP to the SARS-COV2 helicase enzyme .
    FWM-1

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