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Swell

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

2

Biochemical Assay Reagents

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-A0104
    HPMC
    3 Publications Verification

    Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000

    		 Others Others
    HPMC (Hypromellose) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices.
    HPMC
  • HY-W250120
    Konjac glucomannan (Viscosity≥15000mPa.s)

    		Biochemical Assay Reagents Others
    Konjac glucomannan (Viscosity≥15000mPa.s) is an acetylated (1-4)-beta-D-glucomannan extracted from the tuber of konjac or konjac root. In Japan, it is a dietary supplement intended to reduce calorie intake because it swells in water.
    Konjac glucomannan (Viscosity≥15000mPa.s)
  • HY-A0104J
    HPMC (Type II,Viscosity:5mPa.s)

    Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s)

    		 Biochemical Assay Reagents Others
    HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior .
    HPMC (Type II,Viscosity:5mPa.s)
  • HY-109127
    Berotralstat

    BCX7353

    		 Ser/Thr Protease Others
    Berotralstat (BCX7353) is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .
    Berotralstat
  • HY-109127A
    Berotralstat dihydrochloride

    BCX7353 dihydrochloride

    		 Ser/Thr Protease Others
    Berotralstat dihydrochloride is a low toxicity, effective, highly specific, second-generation, synthetic and orally active plasma kallikrein inhibitor used for the research of hereditary angioedema (HAE) attacks. Berotralstat dihydrochloride works by blocking the enzymatic activity of plasma kallikrein in releasing bradykinin, the major biologic peptide that promotes swelling and pain associated with attacks of HAE .
    Berotralstat dihydrochloride
  • HY-Y0756
    Sodium bicarbonate

    Sodium hydrogen carbonate

    		 Biochemical Assay Reagents Others
    Sodium bicarbonate, also known as baking soda, sodium bicarbonate, or sodium bicarbonate, is neutral to slightly alkaline. And it is susceptible to moisture and decomposition in the air. Sodium bicarbonate is widely used in food, pharmaceutical, cosmetics and other fields, the main uses include buffer, seasoning, disinfectant, pharmaceutical and proton gradient regulator. In the food industry, it is often used as a flour starter or leavening agent to make food swell up and become softer. Sodium bicarbonate is also commonly used as an antacid to suppress gastrointestinal disorders, neutralize stomach acid and reduce stomach discomfort.
    Sodium bicarbonate
  • HY-103371
    DCPIB
    5 Publications Verification

    		 Chloride Channel Potassium Channel Neurological Disease
    DCPIB is a selective, reversible and potent inhibitor of volume-regulated anion channels (VRAC). DCPIB voltage-dependently activates potassium channels TREK1 and TRAAK, and inhibits TRESK, TASK1 and TASK3 (IC50s: 0.14, 0.95, 50.72 μM, respectively). DCPIB is also a selective blocker of swelling-induced chloride current (ICl,swell), with an IC50 of 4.1 μM. DCPIB is a useful tool for investigating structure-function studies of K2P channels .
    DCPIB

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