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TBCB

" in MedChemExpress (MCE) Product Catalog:

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Inhibitors & Agonists

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Recombinant Proteins

Cat. No. Compare Product Name Species Source
  • HY-P77331
    CKAP1/TBCB Protein, Human (His)

    Tubulin-folding cofactor B; Cytoskeleton-associated protein 1; TBCB; CG22; CKAP1

    		 Human E. coli
    CKAP1/TBCB protein plays a pivotal role in the tubulin folding pathway, binding to alpha-tubulin folding intermediates after their chaperonin interaction, crucial for tubulin heterodimer transition. It regulates heterodimer dissociation, potentially acting as a negative regulator of axonal growth. The supercomplex, formed with cofactors A to E, captures and stabilizes tubulin, releasing committed polypeptides to the native state. CKAP1/TBCB's interactions with GAN and DCTN1 extend its functional roles in cellular processes. CKAP1/TBCB Protein, Human (His) is the recombinant human-derived CKAP1/TBCB protein, expressed by E. coli, with N-His labeled tag. The total length of CKAP1/TBCB Protein, Human (His) is 244 a.a., with molecular weight of 33-37 kDa.

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