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TNFSF9

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  • HY-P76704
    4-1BBL/TNFSF9 Protein, Rat (HEK293, Fc)

    Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand

    		 Rat HEK293
    4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Rat (HEK293, Fc) is a recombinant protein with a N-Terminal Fc label, It consists of 203 amino acids (P106-G308) and is produced in HEK293 cells.
  • HY-P76705
    4-1BBL/TNFSF9 Protein, Rat (HEK293, His)

    Tumor necrosis factor ligand superfamily member 9; CD137L; 4-1BB Ligand

    		 Rat HEK293
    4-1BBL (4-1BB ligand) is a type II membrane protein of the TNF superfamily, is expressed on antigen-presenting cells. 4-1BB with 4-1BBL can induce T-cell expansion, cytokine induction, differentiation, and upregulation of anti-apoptotic genes as well as protect T cells from activation-induced cell death (AICD). 4-1BBL stimulates T cell proliferation and induces effective anti-tumor immune responses. 4-1BBL is an immunostimulant molecule that interacts with the 4-1BB high-affinity receptor during the antigen presentation, providing costimulatory signals to both CD4+ and CD8+ T cells through the activation of NF-kB, c-Jun, and p38 downstream pathways, triggering pleiotropic effects on the immune system. 4-1BBL/TNFSF9 Protein, Rat (HEK293, His) is a recombinant protein with a N-Terminal His label, It consists of 203 amino acids (P106-G308) and is produced in HEK293 cells.

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