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  3. SRT 1720 hydrochloride

SRT 1720 (x hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

For research use only. We do not sell to patients.

SRT 1720 hydrochloride Chemical Structure

SRT 1720 hydrochloride Chemical Structure

CAS No. : 1001645-58-4

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Top Publications Citing Use of Products

    SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Exp Eye Res. 2023 Apr 2;109464.  [Abstract]

    SRT1720 (1 μM; 1 h) reverses UVA (Using ultraviolet A)-inhibited expression of PGC-1α, NRF2 and TFAM in B4G12 cells.

    SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Exp Eye Res. 2023 Apr 2;109464.  [Abstract]

    SRT1720 (1 μM; 1 h) effectively decreases the levels of cell death and ROS accumulation in the UVA (Using ultraviolet A)-irradiated B4G12 cells.

    SRT 1720 hydrochloride purchased from MedChemExpress. Usage Cited in: Toxicol Lett. 2016 Dec 15;264:1-11.  [Abstract]

    The HNF1α, FXR, Mrp2 and Bsep protein levels are decreased after EE administration and significantly increased by SRT1720 in a dose dependent manner, which is in accordance with the mRNA levels.
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    Description

    SRT 1720 (x hydrochloride) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

    In Vitro

    SRT1720 is a selective activator of SIRT1 with EC50 of 0.16 μM, more than 230 times less potent than SIRT2 and SIRT3.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    Formula

    C25H23N7OS.xHCl

    CAS No.
    SMILES

    O=C(NC1=C(C=CC=C1)C2=CN3C(SC=C3CN4CCNCC4)=N2)C5=NC6=C(N=C5)C=CC=C6.[H]Cl.[x]

    Shipping

    Room temperature in continental US; may vary elsewhere.

    Storage

    Please store the product under the recommended conditions in the Certificate of Analysis.

    Purity & Documentation
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    SRT 1720 hydrochloride Related Classifications

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    The molarity calculator equation

    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    The dilution calculator equation

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
    × = ×
    C1   V1   C2   V2
    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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    Inquiry Information

    Product Name:
    SRT 1720 hydrochloride
    Cat. No.:
    HY-10532A
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