Tomaymycin

Art. -Nr.: HY-N10174: FAQs
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Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria.

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Tomaymycin Chemische Struktur

CAS. Nr. : 35050-55-6

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Beschreibung	Tomaymycin is an antitumor antibiotic. Tomaymycin has antimicrobial activity against Grampositive bacteria^[1]^[2].
IC₅₀ & Target	Antibiotic^[1]^[2]
In Vivo	Tomaymycin, an antiphage antibiotic is produced by cultivation of Streptomyces achromogenes var. tomaymyceticus in a lactose-bouillon medium enriched with yeast extract and phosphate salts. The antiphage activity is strong against Escherichia coli T1, T3 phages and Bacillus subtilis M-2, SP-10 phages. The LD₅₀ (i.p.) of tomaymycin for mice is estimated at 3.0 mg/kg. MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Molekulargewicht	304.34
Formel	C₁₆H₂₀N₂O₄
CAS. Nr.	35050-55-6
SMILES	O=C1N2[C@](C/C(C2)=C\C)([H])[C@H](NC3=CC(O)=C(OC)C=C31)OC
Structure Classification	Antibiotics Disease Research Antibacterial Antibiotics Disease Research Anticancer Phenols Monophenols Antibiotics Other Antibiotics
Initial Source	Microorganisms Streptomyces achromogenes
Versand	Room temperature in continental US; may vary elsewhere.
Speicherung	Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation	Data Sheet (270 KB) Handling Instructions (2659 KB)
Verweise	[1]. F L Boyd, et al. Characterization of a unique tomaymycin-d(CICGAATTCICG)2 adduct containing two drug molecules per duplex by NMR, fluorescence, and molecular modeling studies. Biochemistry. 1990 Mar 6;29(9):2387-403. [Content Brief] [2]. K Arima, et al. Studies on tomaymycin, a new antibiotic. I. Isolation and properties of tomaymycin. J Antibiot (Tokyo). 1972 Aug;25(8):437-44. [Content Brief]

Tomaymycin Related Classifications

Molaritätsrechner
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Die Formel zur Berechnung von Molaritäten

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Diese Gleichung wird häufig abgekürzt als: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tomaymycin35050-55-6Antibioticantitumor antibioticantimicrobial activityGrampositive bacteriaInhibitorinhibitorinhibit

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Tomaymycin

Tomaymycin Related Antibodies

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