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  3. 3'-Fluoro-3'-deoxythymidine

3'-Fluoro-3'-deoxythymidine (Synonyms: Alovudine)

Cat. No.: HY-B1516 Purity: 99.71%
Handling Instructions

3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer.

For research use only. We do not sell to patients.

3'-Fluoro-3'-deoxythymidine Chemical Structure

3'-Fluoro-3'-deoxythymidine Chemical Structure

CAS No. : 25526-93-6

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 83 In-stock
Estimated Time of Arrival: December 31
25 mg USD 75 In-stock
Estimated Time of Arrival: December 31
50 mg USD 120 In-stock
Estimated Time of Arrival: December 31
100 mg USD 160 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

3'-Fluoro-3'-deoxythymidine (Alovudine) is a marker of DNA synthesis that is less susceptible to inflammatory changes than 18F-Fluorodeoxyglucose (FDG) and thus is a better biomarker in pancreatic cancer[1].

Clinical Trial
Molecular Weight

244.22

Formula

C₁₀H₁₃FN₂O₄

CAS No.

25526-93-6

SMILES

OC[[email protected]@H]1[[email protected]@H](F)C[[email protected]](N2C(NC(C(C)=C2)=O)=O)O1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (511.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.0947 mL 20.4733 mL 40.9467 mL
5 mM 0.8189 mL 4.0947 mL 8.1893 mL
10 mM 0.4095 mL 2.0473 mL 4.0947 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (8.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (8.52 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (8.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

3'-Fluoro-3'-deoxythymidineAlovudineOthersInhibitorinhibitorinhibit

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Product Name:
3'-Fluoro-3'-deoxythymidine
Cat. No.:
HY-B1516
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