2. Natural Products
  3. Plants
  4. Asclepiadaceae
  5. Cynanchum otophyllum Schneid．

Cynanchum otophyllum Schneid．

Cynanchum otophyllum Schneid． (10):

Cat. No. 상품명 CAS No. Purity 화학구조
  • HY-N1983
    Caudatin 38395-02-7 99.95%
    Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease.
    Caudatin
  • HY-N1375
    Qingyangshengenin 84745-94-8 99.79%
    Qingyanshengenin (NSC 379666; compound 2), a pregnane glycoside, is a C21 steroidal aglycone isolated from the root of Cynanchumot ophyllum (Asclepiadaceae). Qingyanshengenin has anti-cancer activity.
    Qingyangshengenin
  • HY-N1983R
    Caudatin (Standard) 38395-02-7
    Caudatin (Standard) is the analytical standard of Caudatin (HY-N1983). This product is intended for research and analytical applications. Caudatin is an orally active and brain-penetrant C-21 steroidal found in Cynanchum bungei decne with a variety of biological activities. Caudatin can inhibit cell proliferation, migration, invasion, cause cell phase arrest, induce apoptosis, autophagy, ROS prodution and loss of mitochondrial membrane potential. Caudatin activates PARP, caspase-3, -7, -9, upregulates pro-apoptotic Bad and Bax and downregulates anti-apoptotic Bcl-2 and Bcl-XL. Caudatin suppresses VEGF, FAK phosphorylation, upregulates p21, p27, DR5 protein expression, activates the p38 MAPK, JNK and PPARα/TFEB-mediated autophagy-lysosomal signaling pathways. Caudatin can be used for the research of cancer, inflammation and neurological disease, such as glioma and Alzheimer's disease.
    Caudatin (Standard)
  • HY-N0582
    Otophylloside B 106758-54-7 99.51%
    Otophylloside B, a C-21 steroidal glycoside isolated from Qingyangshen. Otophylloside B protects against Aβ toxicity, which decreases Aβ deposition by decreasing the expression of Aβ at the mRNA level. Otophylloside B has antiepileptic activity.
    Otophylloside B
  • HY-N13315
    Otophylloside J 1015447-50-3
    Otophylloside J is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside J can be used in epilepsy research.
    Otophylloside J
  • HY-N13318
    Otophylloside L 1015447-52-5
    Otophylloside L is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside L can be used in epilepsy research.
    Otophylloside L
  • HY-N13317
    Otophylloside H 1015447-48-9
    Otophylloside H is a pregnane glycosides isolated from the roots of Cynanchum otophyllum. Otophylloside H can be used in epilepsy research.
    Otophylloside H
  • HY-N0581
    Qingyangshengenin A 106644-33-1 99.25%
    Qingyangshengenin A, a C-21 steroidal glycoside isolated from the roots of Cynanchum otophyllum Schneid, has antiepileptic activity.
    Qingyangshengenin A
  • HY-N7456
    Otophylloside O 1326583-08-7
    Otophylloside O is a Steroids product that can be isolated from the roots of Cynanchum otophyllum..
    Otophylloside O
  • HY-N7285
    Otophylloside F 250217-73-3
    Otophylloside F is a Steroids product that can be isolated from the roots of Cynanchum otophyllum..
    Otophylloside F