2. Natural Products
  3. Plants
  4. Hippocastanaceae

Hippocastanaceae

 

Hippocastanaceae (23):

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B2114
    Escin 6805-41-0
    Escin, a natural compound of triterpenoid saponins that can be isolated from horse chestnut (Aesculus hippocastanum) seeds, can be used as a vasoprotective anti-inflammatory, anti-edematous and anti-nociceptive agent.
    Escin
  • HY-B0225
    Methyldopa 555-30-6 99.87%
    Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system.
    Methyldopa
  • HY-N1404
    Sodium aescinate 20977-05-3 99.26%
    Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway.
    Sodium aescinate
  • HY-N0554
    Escin IA 123748-68-5 99.59%
    Escin IA is an oral LOXL2 inhibitor and EMT inhibitor, with selectivity for LOXL2-expressing cells. Escin IA suppresses invasion, migration, and metastasis of breast cancer cells, and acts as the primary anti-TNBC metastasis constituent of Aesculus chinensis Bunge fruit saponin fraction. Escin IA can be used for the research of triple-negative breast cancer, acute inflammation, and ethanol-induced gastric mucosal lesions.
    Escin IA
  • HY-N0555
    Escin IB 26339-90-2 99.05%
    Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity.
    Escin IB
  • HY-N17243
    Aesculinoside C
    Aesculinoside C is an acylated polyhydroxy oleanane-type triterpene saponin that is found in the seeds of Aesculus chinensis.
    Aesculinoside C
  • HY-N16846
    Aesculioside B 106310-33-2
    Aesculioside B is a natural triterpene.
    Aesculioside B
  • HY-N16696
    Escin IVf 249922-20-1
    Escin IVf is a natural triterpene.
    Escin IVf
  • HY-N0556
    Isoescin IA 219944-39-5 98.90%
    Isoescin IA is a triterpenoid saponin isolated from the seeds of Aesculus chinensis. Isoescin IA has anti-HIV-1 protease activity.
    Isoescin IA
  • HY-N16876
    Indole-3-acetic acid N-β-D-xylopyranoside 2506519-33-9
    Indole-3-acetic acid N-β-D-xylopyranoside is a natural alkaloid.
    Indole-3-acetic acid N-β-D-xylopyranoside
  • HY-N16877
    N-(2-Hydroxy-3-methylbutyl)-adenosine 22662-01-7
    N-(2-Hydroxy-3-methylbutyl)-adenosine is a natural alkaloid.
    N-(2-Hydroxy-3-methylbutyl)-adenosine
  • HY-N7303
    Aesculuside B 26339-92-4
    Aesculuside B is a natural product that can be found in Aesculus chinensis?Bunge.
    Aesculuside B
  • HY-179335
    Aescigenin 17806-68-7
    Aescigenin is a triterpenoid saponin compound that can be found in Aesculus hippocastanum. Aescigenin is the main component of sodium β-aescin, a compound that has the functions of reducing tissue edema, improving microcirculation, and anti-inflammation. It can be used in research on Bell's palsy.
    Aescigenin
  • HY-N15152
    Isoaesculioside D 1184581-59-6
    Isoaesculioside D (compound 3) is an agent for preventing or ameliorating skin aging. Isoaesculioside D exhibits an excellent effect on the suppression of formation, or the amelioration, of wrinkles on the skin or sagging skin.
    Isoaesculioside D
  • HY-N13115
    21-Angeloyl-protoaescigenin 35931-54-5
    21-Angeloyl-protoaescigenin (compound 11) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. Protoescigenin 21-tiglate has antitumor activity, with IC50 values of 38.2 μM and 33 μM against MCF-7 and HeLa cells, respectively.
    21-Angeloyl-protoaescigenin
  • HY-N13082
    Deacetylescin Ia 254896-53-2
    Deacetylescin Ia (compound 12) is a deacetylated compound with anti-hyperglycemic effects that can be extracted from the debittered Aesculus and deacetylated at the C-22 position. Deacetylescin Ia (100 mg/kg) can inhibit blood glucose elevation in mouse glucose tolerance tests.
    Deacetylescin Ia
  • HY-N13115A
    Protoescigenin 21-tiglate 7047-43-0
    Protoescigenin 21-tiglate (compound 10) is a glycosidic oleanane-type triterpenoid (BAT) that can be isolated from the acid hydrolysis product (AHP) of the crude extract of Aesculus chinensis seeds. Aesculus-derived triterpenoids (BAT) generally exhibit good antitumor, anti-inflammatory, and anti-Alzheimer's activities. However, the antitumor activity of Protoescigenin 21-tiglate is relatively weak, with IC50 values of >80 μM and 80 μM against MCF-7 and HeLa cells, respectively.
    Protoescigenin 21-tiglate
  • HY-107248
    Escin IIa 158732-55-9
    Escin IIa, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIa has gastroprotections on ethanol-induced gastric mucosal lesions in rats.
    Escin IIa
  • HY-107247
    Escin IIb 158800-83-0
    Escin IIb, isolated from horse chestnut, the seeds of Aesculus hippocastanum L., has positive effects on acute inflammation in animals. Escin IIb showed potent protective effects against ethanol-induced gastric mucosal lesions.
    Escin IIb
  • HY-N7705
    Isoescin Ie 1613506-28-7
    Isoescin Ie is a derivative of Aescine in Aesculi Semen extract.
    Isoescin Ie