1. GPCR/G Protein
    Neuronal Signaling
  2. Adrenergic Receptor
  3. Methyldopa

Methyldopa (Synonyms: L-(-)-α-Methyldopa; MK-351)

Cat. No.: HY-B0225
Handling Instructions

Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system.

For research use only. We do not sell to patients.

Methyldopa Chemical Structure

Methyldopa Chemical Structure

CAS No. : 555-30-6

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Description

Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a prodrug and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

In Vivo

Methyldopa (L-(-)-α-Methyldopa; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 60-day-old male rats[2]
Dosage: 200 mg/kg
Administration: I.p.
Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Clinical Trial
Molecular Weight

211.21

Formula

C₁₀H₁₃NO₄

CAS No.

555-30-6

SMILES

OC1=C(O)C=CC(C[[email protected]@](C)(C(O)=O)N)=C1

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Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

MethyldopaL-(-)-α-MethyldopaMK-351MK351MK 351Adrenergic ReceptorBeta ReceptorantihyoertensiveprodrugmetabolizedhyperglycemicresponseInhibitorinhibitorinhibit

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Methyldopa
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