1. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  2. Adrenergic Receptor Endogenous Metabolite
  3. Methyldopa hydrochloride

Methyldopa hydrochloride  (Synonyms: L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride)

Cat. No.: HY-B0225A
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Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system.

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Methyldopa hydrochloride

Methyldopa hydrochloride Estructura química

No. CAS : 884-39-9

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Descripciòn

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].

IC50 & Target

α adrenergic receptor

 

In Vivo

Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 60-day-old male rats[2]
Dosage: 200 mg/kg
Administration: I.p.
Result: Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Peso molecular

247.68

Fòrmula

C10H14ClNO4

No. CAS
SMILES

OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1.Cl

Structure Classification
Initial Source
Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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Inquiry Information

Nombre del producto:
Methyldopa hydrochloride
Cat. No.:
HY-B0225A
Cantidad:
MCE Japan Authorized Agent: