884-39-9
884-39-9
Chemical Structure
Methyldopa hydrochloride
Synonym(s): L-(-)-α-Methyldopa hydrochloride; MK-351 hydrochloride
- CAS No.: 884-39-9
- Formula:C10H14ClNO4
- Molecular Weight:247.68
IUPAC Name: (S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid hydrochloride
InChIKey: NLRUDGHSXOEXCE-UHFFFAOYSA-N
SMILES: OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1.Cl
Biological Activity: Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].
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Methyldopa hydrochloride | Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system. | |||||||||||||||||||||
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Methyldopa-d3 hydrochloride | Methyldopa-d3 (hydrochloride) is deuterium labeled Methyldopa (hydrochloride). Methyldopa hydrochloride (L-(-)-α-Methyldopa hydrochloride) hydrochloride, a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa hydrochloride is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system. | |||||||||||||||||||||
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References
- [1]. Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56. [Content Brief]
- [2]. Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350. [Content Brief]
