555-30-6
555-30-6
Chemical Structure
Methyldopa
Synonym(s): L-(-)-α-Methyldopa; MK-351
- CAS No.: 555-30-6
- Formula:C10H13NO4
- Molecular Weight:211.21
IUPAC Name: (S)-2-amino-3-(3,4-dihydroxyphenyl)-2-methylpropanoic acid
InChIKey: CJCSPKMFHVPWAR-JTQLQIEISA-N
SMILES: OC1=C(O)C=CC(C[C@@](C)(C(O)=O)N)=C1
Biological Activity: Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Methyldopa | 99.87% | Methyldopa (L-(-)-α-Methyldopa), a potent antihyoertensive agent, is an alpha-adrenergic agonist (selective for α2-adrenergic receptors). Methyldopa is a proagent and is metabolized (α-Methylepinephrine) in the central nervous system. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 1.00
HY-121809DL-Methyldopa -
Similarity Score 1.00
HY-W387035D-α-Methyl DOPA -
Similarity Score 0.86
HY-33549RRacemetirosine (Standard) -
Similarity Score 0.86
HY-W015007Metyrosine -
Similarity Score 0.84
HY-113404DL-Dopa -
Similarity Score 0.84
HY-N0304RL-DOPA (Standard) -
Similarity Score 0.84
HY-N0304S1L-DOPA-13C6 -
Similarity Score 0.84
HY-N0304S2L-DOPA-13C -
Similarity Score 0.84
HY-W096171D-Dopa -
Explore the MedChemAI to find more analogs
References
- [1]. Sweet CS. New centrally acting antihypertensive drugs related to methyldopa and clonidine. Hypertension. 1984;6(5 Pt 2):II51-II56. [Content Brief]
- [2]. Fox GR, et al. The effects of phenobarbital, atropine, L-alpha-methyldopa, and DL-propranolol on dieldrin-induced hyperglycemia in the adult rat. Toxicol Appl Pharmacol. 1985;78(3):342-350. [Content Brief]
