2. GPCR/G Protein Neuronal Signaling Metabolic Enzyme/Protease
  3. Dopamine Receptor Endogenous Metabolite
  4. L-DOPA-13C6

L-DOPA-13C6  (Synonyms: Levodopa-13C6; 3,4-Dihydroxyphenylalanine-13C6)

Cat. No.: HY-N0304S1 Purity: 99.11%
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L-DOPA-13C6 is the 13C-labled L-DOPA. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease.

For research use only. We do not sell to patients.

L-DOPA-<sup>13</sup>C<sub>6</sub>

L-DOPA-13C6 Chemical Structure

CAS No. : 201417-12-1

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Based on 1 publication(s) in Google Scholar

Other Forms of L-DOPA-13C6:

L-DOPA-13C6 Related Antibodies

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Human Endogenous Metabolite Microbial Metabolite

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Description

L-DOPA-13C6 is the 13C-labled L-DOPA[1]. L-DOPA (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. L-DOPA can cross the blood-brain barrier and is converted into dopamine in the brain. L-DOPA has anti-allodynic effects and the potential for Parkinson's disease[2][3][4].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

L-DOPA-13C6 Related Antibodies
Molecular Weight

203.14

Formula

C313C6H11NO4
CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

OC([C@@H](N)C[13C]1=[13CH][13C](O)=[13C]([13CH]=[13CH]1)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 10 mg/mL (49.23 mM; ultrasonic and adjust pH to 1 with 1 M HCl)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 4.9227 mL 24.6136 mL 49.2271 mL
5 mM 0.9845 mL 4.9227 mL 9.8454 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 4.9227 mL 24.6136 mL 49.2271 mL 123.0678 mL
5 mM 0.9845 mL 4.9227 mL 9.8454 mL 24.6136 mL
10 mM 0.4923 mL 2.4614 mL 4.9227 mL 12.3068 mL
15 mM 0.3282 mL 1.6409 mL 3.2818 mL 8.2045 mL
20 mM 0.2461 mL 1.2307 mL 2.4614 mL 6.1534 mL
25 mM 0.1969 mL 0.9845 mL 1.9691 mL 4.9227 mL
30 mM 0.1641 mL 0.8205 mL 1.6409 mL 4.1023 mL
40 mM 0.1231 mL 0.6153 mL 1.2307 mL 3.0767 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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L-DOPA-13C6 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

L-DOPA-13C6201417-12-1Levodopa-13C6 3,4-Dihydroxyphenylalanine-13C6Dopamine ReceptorEndogenous MetaboliteInhibitorinhibitorinhibit

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