- Natural Products
- Plants
- Euphorbiaceae
- Ricinus communis L.
Ricinus communis L.
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Ricinus communis L. (6)
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- Formula: C18H34O3
- Molecular Weight: 298.46
Ricinoleic acid (purity≥85%), a hydroxy fatty acid, is an attractive feedstock for the production of high-performance lubricants, cosmetics, polymers, surfactants, and coatings. Ricinoleic acid is the main active ingredient of Castor oil (HY-107799). Ricinoleic acid is the agonist for prostaglandin EP3 receptor (EP3 receptor) (EC50 in MEG-01 is 0.5 μM), that causes laxative effects and uterine contraction. Ricinoleic acid exhibits antianxiety-like, anti-inflammatory and pro-inflammatory properties.
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- Formula: C8H8N2O2
- Molecular Weight: 164.16
Ricinine is a central nervous system stimulant found in Ricinus communis. Ricinine binds near the benzodiazepine site of the GABAA receptor, reducing benzodiazepine binding affinity through an allosteric effect, and shows no interaction with AMPA, 5-HT1A, muscarinic receptors, or α1 adrenergic receptors. Ricinine improves memory consolidation in mice at low doses, while at high doses it induces seizures, an effect that is selectively inhibited by diazepam. Ricinine shortens the lifespan of Anopheles mosquitoes through sugar feeding and promotes the development of Plasmodium falciparum in mosquitoes. Ricinine is used in research related to epilepsy, amnesia, and malaria.
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- Formula: C7H6N2O2
- Molecular Weight: 150.13
N-Demethylricinine is a ricinine, can be interconverted with ricinine in senescent and green castor plant leaves. Ricinine, is a α-pyridone alkaloid biosynthetically related to the pyridine nucleotide cycle. The alkaloid catabolism of ricinine is associated with aging process.
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- Formula: C8H8N2O2
- Molecular Weight: 164.16
Ricinine (Standard) is the analytical standard of Ricinine. This product is intended for research and analytical applications. Ricinine exhibits hepatoprotection in CCl4 -induced liver damage.
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