1. GPCR/G Protein
  2. Neuropeptide Y Receptor

Neuropeptide Y (29-64), amide, human TFA 

Cat. No.: HY-P0198A Purity: 95.02%
Handling Instructions

Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Neuropeptide Y (29-64), amide, human TFA Chemical Structure

Neuropeptide Y (29-64), amide, human TFA Chemical Structure

Size Price Stock Quantity
1 mg USD 180 In-stock
Estimated Time of Arrival: December 31
5 mg USD 720 In-stock
Estimated Time of Arrival: December 31
10 mg   Get quote  
50 mg   Get quote  

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Other Forms of Neuropeptide Y (29-64), amide, human TFA:

  • Biological Activity

  • Protocol

  • Technical Information

  • Purity & Documentation

  • References

Description

Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

In Vitro

It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to protect cortical neurons from Aβ25-35 toxicity. 2 μM NPY abolishes the toxic effects of Aβ25-35 at 24 and 48 h. The same effect on neuronal survival is observed in neurons exposed to 1 μM and 0.5 μM Neuropeptide Y (29-64), amide, human (TFA) pretreatments. Pretreatment with Neuropeptide Y (29-64), amide, human (TFA) Increases NGF Synthesis, reduces NGF mRNA, and restores NGF release in cortical neurons exposed to Aβ35-25[1].

Solvent & Solubility
In Vitro: 

10 mM in H2O

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.2280 mL 1.1401 mL 2.2801 mL
5 mM 0.0456 mL 0.2280 mL 0.4560 mL
10 mM 0.0228 mL 0.1140 mL 0.2280 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Cell Assay
[1]

Primary cortical neurons are preincubated either alone (positive control) or with three concentrations of Neuropeptide Y (29-64), amide, human (TFA) (NPY) (0.5, 1, and 2 μM) for 24 h and then exposed to Aβ25-35 (50 μM) or Aβ35-25 (50 μM) for 48 h[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

References
Molecular Weight

4385.70

Formula

C₁₉₁H₂₈₆F₃N₅₅O₅₉S

Storage
Protect from light, stored under nitrogen
Powder -80°C 2 years
  -20°C 1 year
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Neuropeptide Y (29-64), amide, human TFA
Cat. No.:
HY-P0198A
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Neuropeptide Y (29-64), amide, human TFA

Cat. No.: HY-P0198A