1. GPCR/G Protein
    Neuronal Signaling
  2. Neuropeptide Y Receptor
  3. [D-Arg25]-Neuropeptide Y (human)

[D-Arg25]-Neuropeptide Y (human) 

Cat. No.: HY-P0198B
Handling Instructions

[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) is a Y1 receptor selective agonist. Neuropeptide Y (human) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.

For research use only. We do not sell to patients.

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[D-Arg25]-Neuropeptide Y (human) Chemical Structure

[D-Arg25]-Neuropeptide Y (human) Chemical Structure

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Description

[D-Arg25]-Neuropeptide Y (human) ([D-Arg25] NPY) is a Y1 receptor selective agonist. Neuropeptide Y (human) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity[1].

In Vitro

[D-Arg25]-NPY (1 μM) reversibly hyperpolarizes the membrane potential of hypocretin cells by 9.9 ± 1.4 mV (data not shown; p < 0.01; n = 10[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Intracerebroventricular (icv) administration of [D-Arg25]NPY stimulates food intake in freely-feeding rats[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

4271.68

Formula

C₁₈₉H₂₈₅N₅₅O₅₇S

Sequence Shortening

YPSKPDNPGEDAPAEDMARYYSAL-{D-Arg}-HYINLITRQRY-NH2

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

[D-Arg25]-Neuropeptide Y (human)Neuropeptide Y ReceptorNPY receptorAlzheimer'sdiseasecorticalβ-AmyloidfoodintakeInhibitorinhibitorinhibit

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Product Name:
[D-Arg25]-Neuropeptide Y (human)
Cat. No.:
HY-P0198B
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