2. Infection

Infection

Infection

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Infection is a pathophysiological process that involves the invasion and colonization of a living organism (host) by disease-causing infectious agents, the reaction of host tissues to these agents and the toxins they produce, and the transmission of infectious agents to other hosts. Common infectious agents include viruses, viroids, prions, bacteria, nematodes, arthropods, and other macroparasites such as tapeworms. Hosts can fight infections using their immune system. Mammals often engage both innate and adaptive immune systems to eliminate infectious agents or inhibit their growth and transmission. When infection occurs, anti-infective drugs can suppress the infection. Several broad types of anti-infective drugs exist, depending on the type of organism targeted; they include antibacterial (antibiotic), antiviral, antifungal and antiparasitic agents.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-156251
    Antifungal agent 74 2856379-97-8 98%
    Antifungal agent 74 (compound 3c) is a potent antifungal agent that displays excellent fungicidal activity against C. arachidicola and R. solani. Antifungal agent 74 exerts its fungicidal activity by disrupting steroid biosynthesis and ribosome biogenesis in eukaryotes.
    Antifungal agent 74
  • HY-156252
    Antifungal agent 75 3013580-23-6 98%
    Antifungal agent 75 (compound 6r) is a potent antifungal agent against Candida albicans. Antifungal agent 75 significantly inhibits the formation of C. albicans biofilm, increases the permeability of the cell membrane, reduces the ergosterol level of the cell membrane, damages the membrane structure, and destroys the integrity of the cell structure to exert excellent antifungal activity.
    Antifungal agent 75
  • HY-156256
    Insecticidal agent 4 2989908-99-6 98%
    Insecticidal agent 4 (compound IA-8) is an aryl isoxazoline derivative with insecticidal activity against M. separate.
    Insecticidal agent 4
  • HY-156270
    SDH-IN-9 98%
    SDH-IN-9 (compound Ip) is a potent inhibitor of Succinate Dehydrogenase. SDH-IN-9 shows fungicidal activity against Fusarium graminearum Schw with the EC50 of 0.93 μg/mL.
    SDH-IN-9
  • HY-156272
    HBV-IN-41 1967002-25-0 98%
    HBV-IN-41 (compound 45) is a potent and orally active Hepatitis B Virus (HBV) inhibitor, with an EC50 of 0.027μM.
    HBV-IN-41
  • HY-156281
    Antifungal agent 76 1615683-57-2 98%
    Antifungal agent 76 (compound 23h) exhibits potent activities and a broad antifungal spectrum with low MICs of 0.25-16 μg/mL. Antifungal agent 76 might achieve its rapid fungicidal activity by disrupting the fungal cell membrane.
    Antifungal agent 76
  • HY-156282
    Antibacterial agent 158 2804045-21-2 98%
    Antibacterial agent 158 (compound 6c), a Micrococcin analogue, and is effective against impetigo and C. difficile infection (CDI).
    Antibacterial agent 158
  • HY-156283
    Antibacterial agent 159 2804044-53-7 98%
    Antibacterial agent 159 (Compound 6d) is an antibiotic. Antibacterial agent 159 can effective against impetigo and C. difficile infection (CDI). Antibacterial agent 159 has no observed recurrence for C. difficile and exertes a minimal impact on the beneficial gut microbiome.
    Antibacterial agent 159
  • HY-156288
    Anti-Influenza agent 5 98%
    Anti-Influenza agent 5 (Compound IIB-2), chalcone-like derivative, is an influenza nuclear export inhibitor. Anti-Influenza agent 5 has inhibitory effects on oseltamivir-resistant strains. Anti-Influenza agent 5 can impede virus proliferation by blocking the export of influenza virus nucleoprotein.
    Anti-Influenza agent 5
  • HY-156289
    Anti-MRSA agent 8 3118-36-3 98%
    Anti-MRSA agent 8 (Compound 7g) is a DAPG derivative with strong antibacterial activity. Anti-MRSA agent 8 assertes its activity by targeting bacterial cell membranes. Anti-MRSA agent 8 can be used for the research of methicillin-resistant Staphylococcus aureus (MRSA).
    Anti-MRSA agent 8
  • HY-156291
    XSJ2-46 2265911-12-2 98%
    XSJ2-46, 5'-amino NI analog, is an antiviral agent. XSJ2-46 has anti-Zika virus activity. XSJ2-46 exhibits reasonable inhibition of RNA-dependent RNA polymerases (RdRp) with an IC50 value of 8.78 μM.
    XSJ2-46
  • HY-156325
    SARS-CoV-2-IN-62 2350285-18-4 98%
    SARS-CoV-2-IN-62 (Compound R3b) is an inhibitor of SARS-CoV-2 replication and has low cytotoxicity. SARS-CoV-2-IN-62 inhibits viral replication in Vero E6 cells and Calu-3 cells, with EC50 values of 2.97 μM and 3.82 μM, respectively.
    SARS-CoV-2-IN-62
  • HY-156330
    HIV-IN-9 98%
    HIV-IN-9 (Compound 2b) is a HIV inhibitor (IC50: 6.65 μg/mL), and has high binding affinity with HIV-RT. HIV-IN-9 also inhibits CYP3A4, CYP1A2, CYP2C1, and CYP2D6.
    HIV-IN-9
  • HY-156337
    SARS-CoV-2-IN-63 2350285-21-9 98%
    SARS-CoV-2-IN-63 (Compound R3e) is an inhibitor of SARS-CoV-2 replication and has low cytotoxicity. SARS-CoV-2-IN-63 inhibits viral replication in Vero E6 cells and Calu-3 cells, with EC50 values of 1.99 μM and 1.92 μM, respectively.
    SARS-CoV-2-IN-63
  • HY-156338
    Laccase-IN-2 3063979-74-5 98%
    Laccase-IN-2 is an inhibitor of laccase. Laccase-IN-2 has excellent antifungal activity against Magnaporthe oryzae in vitro and in vivo.
    Laccase-IN-2
  • HY-156361
    Tuberculosis inhibitor 11 98%
    Tuberculosis inhibitor 11 (Compound 14) can sensitize the antimycobacterial activity of the antitubercular agent.
    Tuberculosis inhibitor 11
  • HY-156369
    Urease-IN-9 98%
    Urease-IN-9 (Compound 1e) is an urease inhibitor (IC50: 19.5?μM).
    Urease-IN-9
  • HY-156439
    Antibiofilm agent-2 2977230-63-8 98%
    Antibiofilm agent-2 (compound 4T) is a potent biofilm inhibitor with an IC50 of 3.6 μM. Antibiofilm agent-2 inhibits the quorum sensing system and iron homeostasis as antibacterial synergists against Pseudomonas aeruginosa.
    Antibiofilm agent-2
  • HY-156441
    SARS-CoV-2-IN-65 98%
    SARS-CoV-2-IN-65 (compound 2f (81)) is a potent,orally active and reversible SARS-CoV-2 entry inhibitor. SARS-CoV-2-IN-65 inhibits the pseudovirus entry in a ACE2-dependent pathway, via mainly inhibiting RBD:ACE2 interaction and TMPRSS2 activity in Calu-3 cells.
    SARS-CoV-2-IN-65
  • HY-156459
    SARS-CoV-2 Mpro-IN-12 370583-15-6 98%
    SARS-CoV-2 Mpro-IN-12 (compound D026) is a SARS-CoV-2 main protease (Mpro) inhibitor with antiviral activities.
    SARS-CoV-2 Mpro-IN-12
Cat. No. Product Name / Synonyms Application Reactivity