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Cat. No.: HY-156281

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Antifungal agent 76

Name: Antifungal agent 76
Brand: MedChemExpress
SKU: HY-156281
Price: 358.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Antifungal agent 76 (compound 23h) exhibits potent activities and a broad antifungal spectrum with low MICs of 0.25-16 μg/mL. Antifungal agent 76 might achieve its rapid fungicidal activity by disrupting the fungal cell membrane.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 1615683-57-2
화학식: C₁₇H₂₀O₂
분자량:256.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

Antifungal agent 76 Chemical Structure

CAS No.: 1615683-57-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
HUVEC	CC₅₀	19.4 μg/mL Compound: 23h	Cytotoxicity against HUVEC cells assessed as inhibition of cell viability incubated for 24 hrs by CCK-8 assay Cytotoxicity against HUVEC cells assessed as inhibition of cell viability incubated for 24 hrs by CCK-8 assay	[PMID: 37788549]

In Vitro

Antifungal agent 76 (compound 23h) exhibits significant inhibition against some virulence factors of Cryptococcus neoformans, low toxicity to normal human cells, as well as favorable pharmacokinetic and drug-like properties^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1615683-57-2
분자량 256.34
화학식 C₁₇H₂₀O₂
SMILES

CCCCCC1=CC=C(C=C1)C2=CC(O)=CC(O)=C2
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu JC, et al. Natural phytoalexins inspired the discovery of new biphenyls as potent antifungal agents for treatment of invasive fungal infections. Eur J Med Chem. 2023 Sep 27;261:115842. [Content Brief]

Calculators

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Mass Mass

Concentration Concentration

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Molecular Weight Molecular Weight

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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