Antifungal agent 76
Antifungal agent 76 (compound 23h) exhibits potent activities and a broad antifungal spectrum with low MICs of 0.25-16 μg/mL. Antifungal agent 76 might achieve its rapid fungicidal activity by disrupting the fungal cell membrane.
For research use only. We do not sell to patients.
- CAS No.: 1615683-57-2
- Formula: C17H20O2
- Molecular Weight:256.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HUVEC | CC50 |
19.4 μg/mL
Compound: 23h
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Cytotoxicity against HUVEC cells assessed as inhibition of cell viability incubated for 24 hrs by CCK-8 assay
Cytotoxicity against HUVEC cells assessed as inhibition of cell viability incubated for 24 hrs by CCK-8 assay
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[PMID: 37788549] |
Antifungal agent 76 (compound 23h) exhibits significant inhibition against some virulence factors of Cryptococcus neoformans, low toxicity to normal human cells, as well as favorable pharmacokinetic and drug-like properties[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1615683-57-2
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Molecular Weight 256.34
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Formula C17H20O2
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SMILES
CCCCCC1=CC=C(C=C1)C2=CC(O)=CC(O)=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Antifungal agent 76 Related Classifications
HY-156281 Related Classifications
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