2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-174576
    Human MYDGF mRNA 98%
    Human MYDGF mRNA encodes the human myeloid derived growth factor (MYDGF) protein. MYDGF was previously thought to support proliferation of lymphoid cells and was considered an interleukin.
    Human MYDGF mRNA
  • HY-174586
    Human LTBR mRNA 98%
    Human LTBR mRNA encodes the human lymphotoxin beta receptor (LTBR) protein, a member of the tumor necrosis factor receptor superfamily. LTBR plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death.
    Human LTBR mRNA
  • HY-174587
    Human LTB mRNA 98%
    Human LTB mRNA encodes the human lymphotoxin beta (LTB) protein, a type II membrane protein of the TNF family. LTB is an inducer of the inflammatory response system and also involved in normal development of lymphoid tissue.
    Human LTB mRNA
  • HY-174588
    Human LTA mRNA 98%
    Human LTA mRNA encodes the human lymphotoxin alpha (LTA) protein, a member of the tumor necrosis factor family. LTA mediates a large variety of inflammatory, immunostimulatory, and antiviral responses. It involves in the formation of secondary lymphoid organs during development and plays a role in apoptosis.
    Human LTA mRNA
  • HY-174595
    Human IL9R mRNA 98%
    Human IL9R mRNA encodes the human interleukin 9 receptor (IL9R) protein, a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9).
    Human IL9R mRNA
  • HY-174596
    Human IL9 mRNA 98%
    Human IL9 mRNA encodes the human interleukin 9 (IL9) protein, a cytokine that acts as a regulator of a variety of hematopoietic cells. IL9 stimulates cell proliferation and prevents apoptosis.
    Human IL9 mRNA
  • HY-174597
    Human IL7R mRNA 98%
    Human IL7R mRNA encodes the human interleukin 7 receptor (IL7R) protein, a receptor for interleukin 7 (IL7). IL7R has been shown to play a critical role in V(D)J recombination during lymphocyte development.
    Human IL7R mRNA
  • HY-174598
    Human IL7 mRNA 98%
    Human IL7 mRNA encodes the human interleukin 7 (IL7) protein, a cytokine that is important for B and T cell development. IL7 plays an essential role in lymphoid cell survival, and in the maintenance of naive and memory T cells.
    Human IL7 mRNA
  • HY-174599
    Human IL6R mRNA 98%
    Human IL6R mRNA encodes the human interleukin 6 receptor (IL6R) protein, a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response.
    Human IL6R mRNA
  • HY-174600
    Human IL6 mRNA 98%
    Human IL6 mRNA encodes the human interleukin 6 (IL6) protein, a cytokine that functions in inflammation and the maturation of B cells. IL6 has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
    Human IL6 mRNA
  • HY-174601
    Human IL5RA mRNA 98%
    Human IL5RA mRNA encodes the human interleukin 5 receptor subunit alpha (IL5RA) protein, an interleukin 5 specific subunit of a heterodimeric cytokine receptor. IL5RA has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4.
    Human IL5RA mRNA
  • HY-174602
    Human IL5 mRNA 98%
    Human IL5 mRNA encodes the human interleukin 5 (IL5) protein, a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL5 plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases.
    Human IL5 mRNA
  • HY-174603
    Human IL4R mRNA 98%
    Human IL4R mRNA encodes the human interleukin 4 receptor (IL4R) protein, a type I transmembrane protein that can bind interleukin 4 and interleukin 13 to regulate IgE production. IL4R also can bind interleukin 4 to promote differentiation of Th2 cells.
    Human IL4R mRNA
  • HY-174604
    Human IL4 mRNA
    Human IL4 mRNA encodes the human interleukin 4 (IL4) protein, a pleiotropic cytokine produced by activated T cells. IL4 is considered an important cytokine for tissue repair, counterbalancing the effects of proinflammatory type 1 cytokines, however, it also promotes allergic airway inflammation. Moreover, IL-4 mediates and regulates a variety of human host responses such as allergic, anti-parasitic, wound healing, and acute inflammation.
    Human IL4 mRNA
  • HY-174605
    Human IL3RA mRNA 98%
    Human IL3RA mRNA encodes the human interleukin 3 receptor subunit alpha (IL3RA) protein, an interleukin 3 specific subunit of a heterodimeric cytokine receptor.
    Human IL3RA mRNA
  • HY-174606
    Human IL34 mRNA 98%
    Human IL34 mRNA encodes the human interleukin 34 (IL34) protein, a cytokine that promotes the differentiation and viability of monocytes and macrophages through the colony-stimulating factor-1 receptor (CSF1R).
    Human IL34 mRNA
  • HY-174607
    Human IL33 mRNA 98%
    Human IL33 mRNA encodes the human interleukin 33 (IL33) protein, a cytokine that binds to the IL1RL1/ST2 receptor. IL33 is involved in the maturation of Th2 cells and the activation of mast cells, basophils, eosinophils and natural killer cells.
    Human IL33 mRNA
  • HY-174608
    Human IL32 mRNA 98%
    Human IL32 mRNA encodes the human interleukin 32 (IL32) protein, a member of the cytokine family. IL32 induces the production of TNFalpha from macrophage cells.
    Human IL32 mRNA
  • HY-174609
    Human IL31 mRNA 98%
    Human IL31 mRNA encodes the human interleukin 31 (IL31) protein, which may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma.
    Human IL31 mRNA
  • HY-174610
    Human IL3 mRNA 98%
    Human IL3 mRNA encodes the human interleukin 3 (IL3) protein, a potent growth promoting cytokine. IL3 is capable of supporting the proliferation of a broad range of hematopoietic cell types. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders.
    Human IL3 mRNA
Cat. No. Product Name / Synonyms Application Reactivity