Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1735):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W008086

H-Thr-OMe hydrochloride		98.0%
H-Thr-OMe.HCl is a threonine derivative.

HY-W008464

H-Thr(Me)-OH		≥98.0%
H-Thr(Me)-OH is a threonine derivative.

HY-W007020

Fmoc-Lys-OAll.HCl		99.26%
Fmoc-Lys-OAll.HCl is a lysine derivative.

HY-W018850

L-Isovaline		99.90%
L-Isovaline is a valine derivative.

HY-W010366

N-Methyl-L-threonine		99.70%
N-Methyl-L-threonine is a threonine derivative.

HY-W008383

H-Glu(OtBu)-OMe.HCl		98.0%
H-Glu(OtBu)-OMe.HCl is a glutamic acid derivative.

HY-W013678

H-Glu(OMe)-OH		98.0%
H-Glu(OMe)-OH is a glutamic acid derivative.

HY-W011913

Boc-Phg-OH		99.73%
Boc-Phg-OH is a Glycine (HY-Y0966) derivative.

HY-W013123

Fmoc-D-Phe(4-CF3)-OH		99.09%
Fmoc-D-Phe(4-CF3)-OH is Phenylalanine derivative. Fmoc-D-Phe(4-CF3)-OH can be used for the research of peptide inhibitors of protein-protein interactions.

HY-Y1167

N-tert-Butoxycarbonyl-N-methylalanine		98.0%
N-tert-Butoxycarbonyl-N-methylalanine is an alanine derivative.

HY-W018717

Boc-Gly-Pro-OH		99.9%
Boc-Gly-Pro-OH is a Glycine (HY-Y0966) derivative.

HY-W041991

Fmoc-Ser-Obzl		99.67%
Fmoc-Ser-Obzl is a serine derivative.

HY-W025811

1-(tert-Butyl) 5-methyl L-glutamate hydrochloride		98.0%
1-(tert-Butyl) 5-methyl L-glutamate hydrochloride is a glutamic acid derivative.

HY-131095

Z-Glu-Tyr-OH		99.42%
Z-Glu-Tyr-OH can be used for synthesis of peptides on a solid support.

HY-W010837

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid		99.85%
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3,3-diphenylpropanoic acid is a phenylalanine derivative.

HY-W005891

H-D-Glu-OtBu		98.0%
H-D-Glu-OtBu is a glutamic acid derivative.

HY-66025

Fmoc-Lys(Me)2-OH hydrochloride
Fmoc-Lys(Me)2-OH HCl is a lysine derivative.

HY-W048708

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-methyl-L-cysteine		99.38%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-S-methyl-L-cysteine is a cysteine derivative.

HY-P4232

H-Gly-Arg-Ala-Asp-Ser-Pro-OH		99.86%
H-Gly-Arg-Ala-Asp-Ser-Pro-OH (GRADSP) is a negative control peptide of GRGDSPK.

HY-78906

N-Benzyl-L-isoleucine		99.49%
N-Benzyl-L-isoleucine is an isoleucine derivative.

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