Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1735):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W008326

Z-Glu(OtBu)-OH		99.94%
Z-Glu(OtBu)-OH is a derivative of glutamate, can be used for molecule, agent, compounds synthesis.

HY-W010788

Boc-His(Trt)-OH		99.84%
Boc-His(Trt)-OH is a histidine derivative.

HY-W008389

Boc-Arg(Pbf)-OH		99.43%
Boc-Arg(Pbf)-OH is an arginine derivative.

HY-P1845A

PACAP-38 (31-38), human, mouse, rat TFA		99.30%
PACAP-38 (31-38), human, mouse, rat TFA is a fragment containing the C-terminal 31-38 fragment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (31-38), human, mouse, rat TFA does not bind to the PACAP receptor.

HY-W011903

L-Alanyl-L-tyrosin		99.94%
L-Alanyl-L-tyrosin is a tyrosine derivative.

HY-W009337

Z-Lys-OH		99.96%
Z-Lys-OH is a lysine derivative.

HY-W018062

H-Sar-OtBu.HCl		98.0%
H-Sar-OtBu.HCl is a Glycine (HY-Y0966) derivative.

HY-76962

(S)-2-Methylpyrrolidine-2-carboxylic acid		98.0%
(S)-2-Methylpyrrolidine-2-carboxylic acid is a proline derivative.

HY-W013745

Fmoc-N-Me-Thr(tBu)-OH		98.98%
Fmoc-N-Me-Thr(tBu)-OH is a threonine derivative.

HY-33228

5-Methyl-DL-tryptophan		99.86%
5-Methyl-DL-tryptophan is aamino acids and their derivatives.

HY-W013779

Fmoc-D-Gly(allyl)-OH		99.98%
Fmoc-D-Gly(allyl)-OH is a Glycine (HY-Y0966) derivative.

HY-W006923

O-(tert-Butyl)-N-Fmoc-L-allothreonine		99.97%
O-(tert-Butyl)-N-Fmoc-L-allothreonine is a threonine derivative.

HY-W014916

L-Methionine methyl ester hydrochloride		≥98.0%
L-Methionine methyl ester hydrochloride is a Methionine (HY-13694) derivative.

HY-W142062

cis-Fmoc-Pro(4-N3)-OH		99.13%
cis-Fmoc-Pro(4-N3)-OH is a proline derivative. cis-Fmoc-Pro(4-N3)-OH is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

HY-W011778

H-Tyr(H2PO3)-OH		99.59%
H-Tyr(H2PO3)-OH is a tyrosine derivative.

HY-B1581

L-Canavanine		98.67%
L-Canavanine is aamino acids and their derivatives.

HY-W013940

DL-Cystine		≥98.0%
DL-Cystine is a cysteine derivative.

HY-113214

3,5-Diiodo-L-tyrosine		99.9%
3,5-Diiodo-L-tyrosine is a tyrosine derivative.

HY-W097122

Fmoc-Gly-Gly-Gly-OH		98.78%
Fmoc-Gly-Gly-Gly-OH is a tripeptide that can be used in peptide synthesis.

HY-131618

Hippuryl-Arg		99.89%
Hippuryl-Arg (Bz-Gly-Arg) is a substrate used for fluorescence detection and is commonly used in biochemical studies, especially in studying enzyme activity. The phenylalanine portion of Hippuryl-Arg is connected by an aromatic side chain, which allows it to be detected under ultraviolet light. Hippuryl-Arg is used to detect enzymes that recognize and cut peptide bonds containing arginine.

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