PACAP-38 (31-38), human, mouse, rat TFA
Based on 1 Customer Validation
PACAP-38 (31-38), human, mouse, rat TFA is a fragment containing the C-terminal 31-38 fragment of PACAP (1-38), human, ovine, rat (HY-P0221). PACAP-38 (31-38), human, mouse, rat TFA does not bind to the PACAP receptor.
For research use only. We do not sell to patients.
- Purity: 99.30%
- Formula: C49H84F3N17O13
- Molecular Weight:1176.29
-
Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
PACAP-38 (31-38), human, mouse, rat TFA has the potential for use in neuroprotection, sympathetic nervous system research, and Alzheimer's disease research.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:NCI-H838 cells
-
Concentration:10 nM
-
Incubation Time:48 hours
-
Result:Increased the number of NCI-H838 cells by 72%.
-
Cell Line:NCI-H838 cells
-
Concentration:100 nM
-
Incubation Time:2 min
-
Result:Increased tyrosine phosphorylation of the EGFR, HER2, and ERK by 377, 299 and 216%, respectively.
Chemical Information
-
Appearance Solid
-
Molecular Weight 1176.29
-
Formula C49H84F3N17O13
-
Color White to off-white
-
Sequence
Tyr-Lys-Gln-Arg-Val-Lys-Asn-Lys-NH2
-
Sequence Shortening
YKQRVKNK-NH2
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
H2O : 100 mg/mL (85.01 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (85.01 mM); Clear solution; Need ultrasonic
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 0.8501 mL | 4.2507 mL | 8.5013 mL | 21.2533 mL |
| 5 mM | 0.1700 mL | 0.8501 mL | 1.7003 mL | 4.2507 mL | |
| 10 mM | 0.0850 mL | 0.4251 mL | 0.8501 mL | 2.1253 mL | |
| 15 mM | 0.0567 mL | 0.2834 mL | 0.5668 mL | 1.4169 mL | |
| 20 mM | 0.0425 mL | 0.2125 mL | 0.4251 mL | 1.0627 mL | |
| 25 mM | 0.0340 mL | 0.1700 mL | 0.3401 mL | 0.8501 mL | |
| 30 mM | 0.0283 mL | 0.1417 mL | 0.2834 mL | 0.7084 mL | |
| 40 mM | 0.0213 mL | 0.1063 mL | 0.2125 mL | 0.5313 mL | |
| 50 mM | 0.0170 mL | 0.0850 mL | 0.1700 mL | 0.4251 mL | |
| 60 mM | 0.0142 mL | 0.0708 mL | 0.1417 mL | 0.3542 mL | |
| 80 mM | 0.0106 mL | 0.0531 mL | 0.1063 mL | 0.2657 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.