Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1735):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W004110

BOC-O-Benzyl-L-threonine		98.57%
BOC-O-Benzyl-L-threonine is a threonine derivative.

HY-W008977

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine		99.57%
N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-O-(phenylmethyl)-L-serine is a serine derivative.

HY-W004063

(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid		99.57%
(S)-3-(Benzyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid is a serine derivative.

HY-W010811

Fmoc-Phe(F5)-OH		99.08%
Fmoc-Phe(F5)-OH is a phenylalanine derivative.

HY-W007052

Fmoc-alpha-allyl-L-alanine		99.71%
Fmoc-alpha-allyl-L-alanine is an Fmoc-protected alanine derivative.

HY-N6655

DL-Methionine methylsulfonium chloride		98.0%
DL-methionine methylsulfonium chloride is a naturally occurring methionine derivative. DL-methionine methylsulfonium chloride protects gastric mucosal from ethanol-induced damage.

HY-W018502

4-Aminobutylphosphonic acid		98.0%
4-Aminobutylphosphonic acid is aamino acids and their derivatives.

HY-W048203

N6-(But-2-enoyl)-L-lysine		99.43%
N6-(But-2-enoyl)-L-lysine is a lysine derivative.

HY-W011088

N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-D-leucine		99.49%
N-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N-methyl-D-leucine is a leucine derivative.

HY-W002436

Fmoc-D-HoPhe-OH		99.83%
Fmoc-D-HoPhe-OH is a phenylalanine derivative.

HY-34666

(4S)-4-Hydroxy-D-proline		99.95%
(4S)-4-Hydroxy-D-proline is a D-proline derivative and aglycon core for synthesis of cell wall O-glycans of the green alga Chlamydomonas reinhardtii.

HY-149449

Poly-L-γ-glutamic acid sodium
Poly-L-γ-glutamic acid sodium is a macromolecular polymer formed by the linkage of glutamic acid residues via peptide bonds between γ-amino and carboxyl groups. Poly-L-γ-glutamic acid sodium plays an important role as a carrier material in compound delivery systems. Poly-L-γ-glutamic acid sodium can deliver Paclitaxel (HY-B0015) to colon cancer cells, reduce cell viability and inhibit the growth of colon cancer spheroids. Poly-L-γ-glutamic acid sodium can be used as a carrier material and in studies related to colon cancer in mice.

HY-W342021

Thr-Leu		99.86%
Thr-Leu is a dipeptide composed of threonine and leucine. Thr-Leu can be hydrolyzed in the peritoneal cavity to generate constituent amino acids, thereby increasing the osmotic pressure of the dialysate. Thr-Leu can be used for the kinetic study of amino acid-based peritoneal dialysis fluids.

HY-W009033

Cbz-Lys(Boc)-OH		99.66%
Cbz-Lys(Boc)-OH is a protected amino acid, primarily utilized in peptide synthesis, protein engineering, and drug development, particularly in research involving lysine residues.

HY-W017501

2-Amino-3-methylsuccinic acid		98.0%
2-Amino-3-methylsuccinic acid is an aspartic acid derivative.

HY-W011003

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiophen-3-yl)propanoic acid		99.35%
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(thiophen-3-yl)propanoic acid is an alanine derivative.

HY-W048913

N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-(2-((5-sulfonaphthalen-1-yl)amino)ethyl)-L-glutamine		98.12%
N2-(((9H-Fluoren-9-yl)methoxy)carbonyl)-N2-(2-((5-sulfonaphthalen-1-yl)amino)ethyl)-L-glutamine is a glutamine derivative.

HY-W041996

H-Asp(Obzl)-OtBu.HCl		99.99%
H-Asp(Obzl)-OtBu.HCl is an aspartic acid derivative.

HY-W008667

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid hydrate		99.74%
(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(tert-butoxy)-5-oxopentanoic acid hydrate is a glutamic acid derivative.

HY-W011001

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid		99.83%
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-cyclohexylpropanoic acid is an alanine derivative.

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