Amino Acid Derivatives

Amino Acid Derivatives are bioactive molecules formed through chemical modifications or metabolic transformations of amino acids. They are widely present in living organisms and play crucial roles in physiological, psychological, and athletic performance.
The functions of these derivatives primarily include enhancing energy supply, regulating neurotransmitters, promoting fat metabolism, and reducing muscle damage. For example, creatine can increase muscle strength, enhance ATP resynthesis, and improve short-duration high-intensity exercise performance; tyrosine, as a precursor of dopamine and norepinephrine, helps enhance cognitive function and improve mood, particularly in sleep deprivation conditions, exhibiting anti-fatigue effects; carnitine facilitates fatty acid oxidation in the heart and skeletal muscles, improving endurance performance; HMB (β-hydroxy-β-methylbutyrate) reduces muscle breakdown and promotes muscle mass gain; while taurine exhibits antioxidant and antihypertensive properties and reduces oxidative stress induced by exercise.
Metabolic abnormalities or improper supplementation of amino acid derivatives may be associated with various diseases. For instance, tyrosine metabolism disorders can disrupt neurotransmitter balance, potentially leading to depression or stress-related disorders; elevated ADMA (asymmetric dimethylarginine) levels can inhibit nitric oxide synthesis, increasing the risk of cardiovascular diseases; carnitine deficiency is linked to certain genetic muscle disorders, impairing fat metabolism and energy production. Additionally, HMB may help slow muscle loss under specific conditions, while taurine intake is associated with improved cardiovascular health. Although some of the effects of these derivatives remain debated, they hold significant potential applications in sports nutrition, neurological regulation, and metabolic health.

References:

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-807. [Content Brief]

Amino Acid Derivatives Related Products (1735):

By Effects:	Inhibitor (1) Chemical (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W141786A

Magnesium L-glutamate tetrahydrate		99.95%
Magnesium L-glutamate tetrahydrate is a cysteine derivative. Magnesium L-glutamate tetrahydrate is a flavor enhancer used to reduce the amount of salt needed in meat products.

HY-W010830

Fmoc-LysTfa-OH		99.80%
Fmoc-Lys(Tfa)-OH is a lysine derivative.

HY-W013874

Boc-D-3-Pal-OH		99.92%
Boc-D-3-Pal-OH is an alanine derivative.

HY-I1111S

Fmoc-L-Val-OH-d₈		99.64%
Fmoc-L-Val-OH-d₈ is a deuterium labeled Fmoc-L-Val-OH (HY-I1111). Fmoc-L-Val-OH is a kind of protect amino acids.

HY-W012713

Ac-D-Ala-OH		98.0%
Ac-D-Ala-OH is an alanine derivative.

HY-60256

(R)-Pyrrolidine-3-carboxylic acid
(R)-Pyrrolidine-3-carboxylic acid is a proline derivative.

HY-103664

Fmoc-1,6-diaminohexane		99.82%
Fmoc-1,6-diaminohexane is an analog of Osw-1 which has the potential for Alzheimer's disease and cancer treatment from patent US 20140135279 A1.

HY-W004098

Boc-D-Met-OH
Boc-D-Met-OH is a Methionine (HY-13694) derivative.

HY-W008353

H-1-Nal-OH		99.49%
H-1-Nal-OH is an alanine derivative.

HY-N2378

(2R,3S)-3-Phenylisoserine hydrochloride
(2R,3S)-3-Phenylisoserine hydrochloride is a serine derivative.

HY-W019205

(4S)-1-Boc-4-amino-D-proline
(4S)-1-Boc-4-amino-D-proline is an amino acid derivative that can be used for compound synthesis.

HY-111434

N6-[(2-Azidoethoxy)carbonyl]-L-lysine		99.9%
N6-[(2-Azidoethoxy) carbonyl]-L-lysine (UAA crosslinker 1) is a click chemistry-reactive amino acid derivative. N6-[(2-Azidoethoxy) carbonyl]-L-lysine mediates the generation of antibody-drug conjugates (ADCs). N6-[(2-Azidoethoxy) carbonyl]-L-lysine is used for site-specific incorporation into recombinant proteins, or for synthesizing chemical probes and tools for biological research.

HY-W012075

H-Cys(pMeOBzl)-OH		98.18%
H-Cys(pMeOBzl)-OH is a cysteine derivative.

HY-W010825

Fmoc-Phe(2-Br)-OH
Fmoc-Phe(2-Br)-OH is a phenylalanine derivative.

HY-W013760

(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid
(R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-2-phenylacetic acid is a Glycine (HY-Y0966) derivative.

HY-W005014

Methyl 2-amino-2-cyclopropylacetate hydrochloride
Methyl 2-amino-2-cyclopropylacetate hydrochloride is a Glycine (HY-Y0966) derivative.

HY-W005308

N-BOC-DL-serine methyl ester		98.0%
N-BOC-DL-serine methyl ester is a Serine derivative. N-BOC-DL-serine methyl ester is used for the synthesis of α,β-dehydro-α-amino acid. N-BOC-DL-serine methyl ester is also used for the synthesis of anti-cancer agent, such as quinazolinone derivative that inhibits PI3K activity, and tricyclic pyrolopyranopyridines that inhibits protein kinase activity.

HY-W063269

(S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate		98.25%
(S)-1-Benzyl 2-methyl 4-oxopyrrolidine-1,2-dicarboxylate is a proline derivative.

HY-P4520

(Trp4)-Kemptide		99.68%
(Trp4)-Kemptide is a peptide substrate for adenosine 3',5'-cyclic monophosphate-dependent protein kinase.

HY-W141774

S-(2-Carboxyethyl)-L-cysteine		98.64%
S-(2-Carboxyethyl)-L-cysteine (S-Carboxyethylcysteine) is a non-protein (modified) sulfur amino acid. S-(2-Carboxyethyl)-L-cysteine is present in Acacia seed. S-(2-Carboxyethyl)-L-cysteine can affect the seed’s protein use in rats. S-(2-Carboxyethyl)-L-cysteine suppresses the methionine-induced growth rate, and has a negative effect on the plasma amino acid levels in rats.

Name
Email *

	Sorry, but the email address you supplied was invalid.