1. Others
  2. Isotope-Labeled Compounds Amino Acid Derivatives
  3. Fmoc-L-Val-OH-d8

Fmoc-L-Val-OH-d8  (Synonyms: FMOC-L-valine-d8; Fmoc-valine-d8)

Cat. No.: HY-I1111S Purity: 99.64%
Handling Instructions Technical Support

Fmoc-L-Val-OH-d8 is a deuterium labeled Fmoc-L-Val-OH (HY-I1111). Fmoc-L-Val-OH is a kind of protect amino acids.

For research use only. We do not sell to patients.

Fmoc-L-Val-OH-d<sub>8</sub>

Fmoc-L-Val-OH-d8 Chemical Structure

CAS No. : 1007834-06-1

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
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Solution
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Solid
5 mg In-stock
10 mg In-stock
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100 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Other Forms of Fmoc-L-Val-OH-d8:

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Description

Fmoc-L-Val-OH-d8 is a deuterium labeled Fmoc-L-Val-OH (HY-I1111). Fmoc-L-Val-OH is a kind of protect amino acids[1][2].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

347.43

Formula

C20H13D8NO4

CAS No.
Unlabeled CAS
Appearance

Solid

Color

White to off-white

SMILES

O=C(O)[C@@](C([2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])([2H])NC(OCC1C2=C(C=CC=C2)C3=C1C=CC=C3)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (287.83 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.8783 mL 14.3914 mL 28.7828 mL
5 mM 0.5757 mL 2.8783 mL 5.7566 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.64%

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.8783 mL 14.3914 mL 28.7828 mL 71.9569 mL
5 mM 0.5757 mL 2.8783 mL 5.7566 mL 14.3914 mL
10 mM 0.2878 mL 1.4391 mL 2.8783 mL 7.1957 mL
15 mM 0.1919 mL 0.9594 mL 1.9189 mL 4.7971 mL
20 mM 0.1439 mL 0.7196 mL 1.4391 mL 3.5978 mL
25 mM 0.1151 mL 0.5757 mL 1.1513 mL 2.8783 mL
30 mM 0.0959 mL 0.4797 mL 0.9594 mL 2.3986 mL
40 mM 0.0720 mL 0.3598 mL 0.7196 mL 1.7989 mL
50 mM 0.0576 mL 0.2878 mL 0.5757 mL 1.4391 mL
60 mM 0.0480 mL 0.2399 mL 0.4797 mL 1.1993 mL
80 mM 0.0360 mL 0.1799 mL 0.3598 mL 0.8995 mL
100 mM 0.0288 mL 0.1439 mL 0.2878 mL 0.7196 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
Fmoc-L-Val-OH-d8
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HY-I1111S
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