2. Signaling Pathways
  3. Others
  4. Drug Derivative

Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Drug Derivative Related Products (3822):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N3165
    O-Acetylcyclocalopin A
    O-Acetylcyclocalopin A is an amino acid analog of cyclocalopin, isolated from the Boletus calopus fungus from Yunnan Province.
    O-Acetylcyclocalopin A
  • HY-N17646
    N-trans-Cinnamoyltyramine
    N-trans-Cinnamoyltyramine is a natural product that can be found in osmanthus fragrans.
    N-trans-Cinnamoyltyramine
  • HY-113509A
    6-epi-Lipoxin A4
    6-epi-Lipoxin A4 is an active compound.
    6-epi-Lipoxin A4
  • HY-N16723
    Demethylbroussin
    Demethylbroussin is a natural flavonoid.
    Demethylbroussin
  • HY-N18211
    1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin
    1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin is a nerve growth factor-enhanced limonoid. 1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin enhances nerve growth factor-mediated neurite outgrowth in PC12 cells. 1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin enhances nerve growth factor-mediated neurite outgrowth.
    1α,3α-Dihydroxyl-7α-tigloyloxy-12α-ethoxylnimbolinin
  • HY-N17191
    Urodiolenone
    Urodiolenone is a natural sesquiterpene.
    Urodiolenone
  • HY-N16781
    Poilaneic acid
    Poilaneic acid is a natural diterpene.
    Poilaneic acid
  • HY-116148
    AHR-11797
    AHR-11797 is an active compound.
    AHR-11797
  • HY-N17038
    2'-O-(2,3-Dihydroxybenzoyl)sweroside
    2'-O-(2,3-Dihydroxybenzoyl)sweroside is a natural iridoid.
    2'-O-(2,3-Dihydroxybenzoyl)sweroside
  • HY-164441
    Anticancer agent 252
    Anticancer agent 252 (compound 1) is a benzamide compound with selective anti-cancer activity against small cell lung cancer (SCLC) cells. Anticancer agent 252 inhibits murine SCLC (mSCLC) cell lines with an average EC50 of 3.21 μM. Anticancer agent 252 also inhibits human SCLC cell lines, H889, H2107, and H128.
    Anticancer agent 252
  • HY-N15573
    7-epi-10-Deacetylcephalomannine
    7-epi-10-Deacetylcephalomannine is a taxol-related compound found in the needles of Taxus sumatrana.
    7-epi-10-Deacetylcephalomannine
  • HY-N18314
    2,4,6-Trihydroxy-5-methoxyacetophenone
    2,4,6-Trihydroxy-5-methoxyacetophenone (Compound 56) is an acetophenone derivative that can be isolated from the trunk bark of Antiaris toxicaria.
    2,4,6-Trihydroxy-5-methoxyacetophenone
  • HY-N7308
    Effususol A
    Effususol A is a natural phenolic compound.
    Effususol A
  • HY-N13755
    Prionidipene A
    Prionidipene A is a natural diterpene.
    Prionidipene A
  • HY-122172
    GSK3-IN-6
    GSK3-IN-6 is an active compound.
    GSK3-IN-6
  • HY-N7282
    Ustusol A
    Ustusol A is a natural sesquiterpene.
    Ustusol A
  • HY-116024
    Dimefuron
    Dimefuron is an active compound.
    Dimefuron
  • HY-159949
    YS10
    YS10 is a Tryptamine (HY-B2132) derivative. YS10 inhibits cell viability of SH-SY5Y cells with an IC50 of 0.44 nM.
    YS10
  • HY-165624B
    (R)-LY-41
    (R)-LY-41, R-enantiomer of LY-41 (HY-165624), is 2-Sminotetralin (HY-W022362) derivative and 8-OH-DPAT (HY-112061) analogue. (R)-LY-41 is a potent and selective 5-HT1A receptor agonist. (R)-LY-41 can reduce the accumulation of 5-hydroxytryptophan (the precursor for 5-HT synthesis) in the rat brain induced by decarboxylase inhibitors (NSD 1015). (R)-LY-41 can lower the body temperature of rats and inhibit the escape response from the cage. (R)-LY-41 can induce the 5-HT behavioral syndrome but is weaker than (S)-LY-41 (HY-165624A). (R)-LY-41 can be used for the research of neurological disease, such as depression and anxiety.
    (R)-LY-41
  • HY-N7159
    3,23-Dioxocycloart-24-en-26-oic acid
    3,23-Dioxocycloart-24-en-26-oic acid is a natural triterpene.
    3,23-Dioxocycloart-24-en-26-oic acid