2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10876):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0684S4
    Vitamin K1-d3
    Vitamin K1-d3 (Phylloquinone-d3; Phytomenadione-d3) is deuterium-labeled Vitamin K1 (HY-N0684).
    Vitamin K1-d<sub>3</sub>
  • HY-W769288
    Pemetrexed disodium-13C5
    Pemetrexed disodium-13C5 (LY231514 disodium-13C5) is the 13C-labeled Pemetrexed disodium (HY-10820A). Pemetrexed disodium (LY231514 disodium) is an antifolate, the Kis of the pentaglutamate of Pemetrexed disodium are 1.3, 7.2, and 65 nM for inhibits thymidylate synthase (TS), dihydrofolate reductase (DHFR), and glycinamide ribonucleotide formyltransferase (GARFT), respectively.
    Pemetrexed disodium-<sup>13</sup>C<sub>5</sub>
  • HY-146579S
    Estrone-3-glucuronide-d4 lithium
    Estrone-3-glucuronide-d4 lithium is the deuterium labeled Estrone-3-glucuronide lithium. Estrone 3-glucuronide is a dominant urinary metabolite of?Estradiol?(HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits.
    Estrone-3-glucuronide-d<sub>4</sub> lithium
  • HY-N10508S
    Calcitroic acid-13C
    Calcitroic acid-13C is the 13C-labeled Calcitroic acid (HY-N10508). Calcitroic acid is a vitamin D receptor (VDR) agonist that can activate VDR-mediated transcription. Calcitroic acid is the main metabolite of 1,25-dihydroxyvitamin D3, with the highest concentrations found in the liver and mucosa of mice, and it has metabolic stability and very low toxicity.
    Calcitroic acid-<sup>13</sup>C
  • HY-W027751S
    2-Methylanisole-d3
    		98.6%
    2-Methylanisole-d3 is the deuterium labeled 2-Methylanisole. 2-Methylanisole is a monomethoxybenzene and acts as an intermediate for the preparation of compounds with methylhydroquinone core.
    2-Methylanisole-d<sub>3</sub>
  • HY-124489S
    2-Hydroxyestradiol-13C6
    2-Hydroxyestradiol-13C6 is the 13C-labeled 2-Hydroxyestradiol. 2-Hydroxyestradiol, a metabolite of 17β-estradiol with minimal estrogenic activity, possesses antioxidant effects and reacts with DNA to form stable adducts and exerts genotoxicity.
    2-Hydroxyestradiol-<sup>13</sup>C<sub>6</sub>
  • HY-50898S3
    Lapatinib-d4-1
    Lapatinib-d4-1 is deuterium labeled Lapatinib. Lapatinib (GW572016) is a potent, orally active inhibitor of the ErbB-2 and EGFR tyrosine kinase domains with IC50 values against purified EGFR and ErbB-2 of 10.2 and 9.8 nM, respectively.
    Lapatinib-d<sub>4</sub>-1
  • HY-150664S
    4-Methoxy-benzoic acid-d3
    4-Methoxy-benzoic acid-d3 is the deuterium labeled 4-Methoxy-benzoic acid.
    4-Methoxy-benzoic acid-d<sub>3</sub>
  • HY-W587411S
    Mono[2-(carboxymethyl)hexyl] phthalate-d4
    Mono[2-(carboxymethyl)hexyl] phthalate-d4 is a deuterium labeled compound.
    Mono[2-(carboxymethyl)hexyl] phthalate-d<sub>4</sub>
  • HY-109077S
    Tigolaner-d4
    Tigolaner-d4 is deuterium labeled Tigolaner. Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity.
    Tigolaner-d<sub>4</sub>
  • HY-W709204
    N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine-d55
    N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine-d5 is the deuterium labeled N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine.
    N2-(S)-1-Carboxy-3-phenylpropyl-L-lysine-d5<sub>5</sub>
  • HY-10466BS
    Daclatasvir-d6 hydrochloride
    Daclatasvir-d6 hydrochloride is deuterated labeled Daclatasvir.
    Daclatasvir-d<sub>6</sub> hydrochloride
  • HY-W777149
    [2-(6-Amino-9H-purin-9-yl)ethanol-d4
    [2-(6-Amino-9H-purin-9-yl)ethanol-d4 is the deuterium labeled 9-(2-Hydroxyethyl)adenine (HY-W105677).
    [2-(6-Amino-9H-purin-9-yl)ethanol-d<sub>4</sub>
  • HY-150674S
    Curcumin-diglucoside tetraacetate-d6
    Curcumin-diglucoside tetraacetate-d6 is the deuterium labeled Curcumin-diglucoside tetraacetate.
    Curcumin-diglucoside tetraacetate-d<sub>6</sub>
  • HY-W111879S
    Oxamic acid hydrazide-15N3
    Oxamic acid hydrazide-15N3 is the 15N3 labeled Oxamic acid hydrazide.
    Oxamic acid hydrazide-<sup>15</sup>N<sub>3</sub>
  • HY-W778171
    2-Benzyloxy-5-nitro-benzoic Acid Benzyl Ester-13C6
    2-Benzyloxy-5-nitro-benzoic Acid Benzyl Ester-13C6 is the 13C-labeled Benzyl 2-(benzyloxy)-5-nitrobenzoate (HY-W702473).
    2-Benzyloxy-5-nitro-benzoic Acid Benzyl Ester-<sup>13</sup>C<sub>6</sub>
  • HY-15498S
    Rimegepant-d4
    Rimegepant-d4 (BMS-927711-d4) is the deuterium labeled Rimegepant (HY-15498). Rimegepant (BMS-927711) is an orally bioavailable and blood-brain barrier permeable antagonist of CGRP and AMY1 receptors, with a pIC50 of 8.01 and a Ki of 0.027 nM for human CGRP receptors. Rimegepant antagonizes cAMP production induced by αCGRP, βCGRP and amylin at CGRP and AMY1 receptors in humans, rats and mice, as well as at rat AMY3 receptors. Rimegepant can be used in research related to migraine.
    Rimegepant-d<sub>4</sub>
  • HY-W740212
    16-Keto 17Beta-estradiol-d5
    16-Keto 17Beta-estradiol-d5 is the deuterium labeled 16-Ketoestradiol (HY-W587691). 6-Ketoestradiol is an active metabolite of the endogenous estrogen estrone.
    16-Keto 17Beta-estradiol-d<sub>5</sub>
  • HY-N11142S
    Gb3-d7 (18:1/18:0)
    		99.9%
    Gb3-d7 (18:1/18:0) (C18 Globotriaosylceramide-d7 (d18:1/18:0)) is deuterium labeled Gb3(18:1/18:0). Gb3(18:1/18:0) (C18 Globotriaosylceramide (d18:1/18:0)) is an ester product.
    Gb3-d<sub>7</sub> (18:1/18:0)
  • HY-B0347S3
    Lacidipine-13C4
    Lacidipine-13C4 is 13C labeled Lacidipine (HY-B0347). Lacidipine is an orally active and highly selective L-type calcium channel blocker that acts on smooth muscle calcium channels, primarily dilates peripheral arteries, reduces peripheral resistance, and has long-lasting anti-hypertensive activity. Lacidipine protects HKCs from apoptosis induced by ATP depletion and recovery by modulating the caspase-3 pathway. Lacidipine can be used in studies of hypertension, atherosclerosis and acute kidney injury (AKI).
    Lacidipine-<sup>13</sup>C<sub>4</sub>