Estrone-3-glucuronide-d4 lithium
Estrone-3-glucuronide-d4 lithium is the deuterium labeled Estrone-3-glucuronide lithium. Estrone 3-glucuronide is a dominant urinary metabolite of?Estradiol?(HY-B0141) and urinary marker for female fertile window prediction. Estrone 3-glucuronide can be used in combination with luteinizing hormone in ovulation prediction kits.
For research use only. We do not sell to patients.
- Formula: C24H25D4LiO8
- Molecular Weight:456.45
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 2479-90-5
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Molecular Weight 456.45
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Formula C24H25D4LiO8
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SMILES
O[C@H]([C@H]([C@@H]([C@@H](C(O[Li])=O)O1)O)O)[C@@H]1OC(C([2H])=C2)=C([2H])C(CC[C@@]3([H])[C@]4([H])CC5([2H])[2H])=C2[C@@]3([H])CC[C@]4(C)C5=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Endocrine Diseases
Endocrine diseases often arise from disrupted hormone production, hormone signaling, or target-tissue responsiveness; for diabetes-focused endocrine disease models, insulin signaling regulates glucose uptake, hepatic glucose output, lipid metabolism, and β-cell compensation. Type 2 diabetes develops through interacting defects in insulin resistance, β-cell dysfunction, adipose inflammation, hepatic glucose overproduction, altered incretin signaling, and ectopic lipid metabolism. A major unresolved question is whether endocrine dysfunction is driven primarily by target-tissue insulin resistance, intrinsic β-cell failure, immune/inflammatory stress, or combined multi-organ failure that differs by disease stage.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Estrone-3-glucuronide-d4 lithium Related Classifications
HY-146579S Related Classifications
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