2. Signaling Pathways
  3. Others
  4. Isotope-Labeled Compounds

Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Related Products (10678):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W140740S
    Hexabromobenzene-13C6
    Hexabromobenzene-13C6 (Perbromobenzene-13C6) is 13C labeled Hexabromobenzene.
    Hexabromobenzene-<sup>13</sup>C<sub>6</sub>
  • HY-W011577S1
    Dibenzo[a,c]anthracene-13C6
    Dibenzo[a,c]anthracene-13C6 (2,3-Benzotriphenylene-13C6) is 13C labeled Benzo[f]tetraphene. Benzo[f]tetraphene (Dibenz[a,c]anthracene) is a polycyclic aromatic hydrocarbon with significant antitumor activity. Benzo[f]tetraphene is used as a luminescent probe in cell biology research and can effectively detect reactive oxygen species in biological systems. Benzo[f]tetraphene can also be used as a potential photosensitizer and shows good application prospects in photodynamic inhibition.
    Dibenzo[a,c]anthracene-<sup>13</sup>C<sub>6</sub>
  • HY-50896S2
    Erlotinib-d4
    Erlotinib-d4 (CP-358774-d4) is deuterium labeled Erlotinib. Erlotinib (CP-358774) is a directly acting EGFR tyrosine kinase inhibitor, with an IC50 of 2 nM for human EGFR. Erlotinib reduces EGFR autophosphorylation in intact tumor cells with an IC50 of 20 nM. Erlotinib is used for the treatment of non-small cell lung cancer. Erlotinib is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Erlotinib-d<sub>4</sub>
  • HY-132353S
    (Rac)-5-Carboxy desisopropyl tolterodine-d7
    (Rac)-5-Carboxy desisopropyl tolterodine-d7 is the deuterium labeled (Rac)-5-Carboxy desisopropyl tolterodine.
    (Rac)-5-Carboxy desisopropyl tolterodine-d<sub>7</sub>
  • HY-10232S
    THIP-d4
    THIP-d4 (Gaboxadol-d4) is the deuterium labeled THIP (HY-10232). THIP (Gaboxadol) is a selective extrasynaptic GABAA receptors (eGABARs) agonist (with blood-brain barrier permeability), shows an EC50 value of 13 μM for δ-GABAAR. THIP induces strong tense GABAA-mediated currents in layer 2/3 neurons, but shows on effect on miniature IPSCs. THIP can be used in studies of sleep disorders.
    THIP-d<sub>4</sub>
  • HY-165693S
    Sodium 2-((2,6-bis(methyl-d3)phenyl-3,4,5-d3amino)-2-oxoethane-1-sulfonate
    Sodium 2-((2,6-bis(methyl-d3)phenyl-3,4,5-d3)amino)-2-oxoethane-1-sulfonate is deuterium labeled Sodium 2-((2,6-dimethylphenyl)amino)-2-oxoethane-1-sulfonate.
    Sodium 2-((2,6-bis(methyl-d<sub>3</sub>)phenyl-3,4,5-d<sub>3</sub>amino)-2-oxoethane-1-sulfonate
  • HY-B0180S2
    Imiquimod-d7
    Imiquimod-d7 (R 837-d7) is deuterium labeled Imiquimod. Imiquimod (R 837), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod exhibits antiviral and antitumor effects in vivo. Imiquimod can be used for the research of external genital, perianal warts, cancer and COVID-19.
    Imiquimod-d<sub>7</sub>
  • HY-34487S3
    1,3-Dimethoxybenzene-d3
    1,3-Dimethoxybenzene-d3 (Resorcinol dimethyl ether-d3) is the deuterium labeled 1,3-Dimethoxybenzene (HY-34487). 1,3-Dimethoxybenzene belongs to the class of organic compounds known as dimethoxybenzenes. 1,3-Dimethoxybenzene is an intermediate in synthesis of organic compounds.
    1,3-Dimethoxybenzene-d<sub>3</sub>
  • HY-144362S
    N-Acetyl-S-(2,5-dimethylbenzene)-L-cysteine-d3
    N-Acetyl-S-(2,5-dimethylbenzene)-L-cysteine-d3 is the deuterium labeled N-Acetyl-S-(2,5-dimethylbenzene)-L-cysteine.
    N-Acetyl-S-(2,5-dimethylbenzene)-L-cysteine-d<sub>3</sub>
  • HY-114553S
    1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d5
    1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d5 (5F-PB-223-Carboxyindolemetabolite-d5) is deuterium labeled 1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid.
    1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid-d<sub>5</sub>
  • HY-W617979S
    3,4-Dichlorodiphenyl ether-13C12
    3,4-Dichlorodiphenyl ether-13C12 is 13C labeled 3,4-Dichlorodiphenyl ether.
    3,4-Dichlorodiphenyl ether-<sup>13</sup>C<sub>12</sub>
  • HY-B0113S4
    Omeprazole-d3 sodium
    Omeprazole-d3 sodium is deuterated labeled Omeprazole (HY-B0113). Omeprazole sodium (H 16868) is an orally active H+,K+-ATPase inhibitor and a proton pump inhibitor. Omeprazole sodium competitively inhibits CYP2C19, CYP3A4, and CYP2C9 activity. Omeprazole sodium inhibits gastric acid secretion and can be used for acid-related gastrointestinal disorders. Omeprazole sodium inhibits pancreatic cancer cell proliferation, induces apoptosis, autophagosome accumulation (elevated LC3-I and LC3-II levels), oxidative stress, and cytogenetic imbalance, modulates lysosomal transport, reduces inflammatory cytokines. Omeprazole sodium alters small intestinal morphology and magnesium absorption, and induces gastric mucosa morphologic changes. Omeprazole sodium aslo has neuroprotective and antibacterial effects.
    Omeprazole-d<sub>3</sub> sodium
  • HY-B0683S
    Limaprost-d3
    Limaprost-d3 (17α,20-dimethyl-δ2-PGE1-d3) is the deuterium labeled Limaprost. Limaprost (OP1206) is a PGE1 analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost pain relief, has antianginal effects, and can be used for ischaemic symptoms research.
    Limaprost-d<sub>3</sub>
  • HY-W744212
    N-Nitroso desloratadine-d4
    N-Nitroso desloratadine-d4 is deuterium labeled N-Nitroso desloratadine.
    N-Nitroso desloratadine-d<sub>4</sub>
  • HY-148036S
    FLT3-IN-16-d1
    FLT3-IN-16-d1 is the deuterium labeled FLT3-IN-16 (HY-148036). FLT3-IN-16 is a potent FLT3 inhibitor with an IC50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia.
    FLT3-IN-16-d<sub>1</sub>
  • HY-W004305S1
    Hexadecanal-d9
    16:0 Aldehyde-d9 is a deuterated fatty aldehyde.
    Hexadecanal-d<sub>9</sub>
  • HY-156250S
    7α-Methylthiol spironolactone-d5
    7α-Methylthiol spironolactone-d5 is deuterated labeled 7α-Methylthiol spironolactone.
    7α-Methylthiol spironolactone-d<sub>5</sub>
  • HY-W011297S2
    Methyl arachidonate-13C4
    Methyl arachidonate-13C4 (Arachidonic acid methyl ester-13C4) is 13C labeled Methyl arachidonate. Methyl arachidonate (Arachidonic acid methyl ester) is a fatty acid methyl ester resulting from the formal condensation of the carboxy group of arachidonic acid with methanol. Methyl arachidonate has activity of human blood serum metabolite.
    Methyl arachidonate-13</sup>C<sub>4</sub>
  • HY-118861S1
    Enclomiphene-d4
    		99.85%
    Enclomiphene-d4 ((E)-Clomiphene-d4) is a deuterium labeled Enclomiphene. Enclomiphen?is a potent and orally active?estrogen receptor?antagonist with antioestrogenic property.
    Enclomiphene-d<sub>4</sub>
  • HY-70057S4
    Safinamide-d5
    Safinamide-d5 (FCE 26743-d5) is deuterium labeled Safinamide. Safinamide is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 μM) over MAO-A (IC50=580 μM). Safinamide also blocks sodium channels and modulates glutamate (Glu) release, showing a greater affinity at depolarized (IC50=8?μM) than at resting (IC50=262?μM) potentials. Safinamide has neuroprotective and neurorescuing effects and can be used for the study of parkinson disease, ischemia stroke etc.al.
    Safinamide-d<sub>5</sub>