Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W303130S

Sinapic acid ethyl ester-d₃
Sinapic acid ethyl ester-d3 is a deuterium labeled sinapic acid ethyl ester.

HY-N0832S1A

L-Histidine-¹³C₆,¹⁵N₃ hydrochloride
L-Histidine-¹³C₆,¹⁵N₃ hydrochloride is the ¹³C and ¹⁵N labled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.

HY-B0002S

Ondansetron-d₃ hydrochloride		98.78%
Ondansetron-d₃ (hydrochloride) is the deuterium labeled Ondansetron hydrochloride. Ondansetron hydrochloride (GR 38032 hydrochloride) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.

HY-W747621

Ethyl formate-¹³C		99%
Ethyl formate-¹³C is ¹³C labeled Ethyl formate.

HY-B0139S

Flucytosine-¹³C,15N₂		98.06%
Flucytosine-¹³C,¹⁵N₂ (NSC 103805-¹³C,¹⁵N₂; Ro 2-9915-¹³C,¹⁵N₂) is a ¹³C- and ¹⁵N-labeled Flucytosine (HY-B0139).

HY-Y0858S2

N,N-Dimethylethylenediamine-d₄ hydrochloride
N,N-Dimethylethylenediamine-d₄ hydrochloride is the deuterium labeled N,N-Dimethylethylenediamin hydrochloride.

HY-13955S3

Telmisartan-d₇		99.57%
Telmisartan-d₇ (BIBR 277-d₇) is a deuterium labeled Telmisartan (HY-13955). Telmisartan is a potent, long lasting antagonist of angiotensin II type 1 receptor (AT1), selectively inhibiting the binding of ¹²⁵I-AngII to AT1 receptors with IC₅₀ of 9.2 nM.

HY-B0198S

Cefaclor-d₅
Cefaclor-d₅ is the deuterium labeled Cefaclor. Cefaclor is an effective antibiotic agent, and specifically binds to penicillin-binding protein 3 (PBP 3).

HY-W705528

2-Bromo-2-methylpropanoic acid-d₆		98.36%
2-Bromo-2-methylpropanoic acid-d₆ (α-Bromoisobutyric acid-d₆) is the deuterium labeled 2-Bromo-2-methylpropanoic acid (HY-W017134).

HY-N0733S

Glucosamine-¹³C hydrochloride		98.13%
Glucosamine-¹³C (hydrochloride) is the ¹³C labeled Glucosamine hydrochloride. Glucosamine hydrochloride (D-Glucosamine hydrochloride) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a

HY-B0192S2

Alfuzosin-d₃		99.90%
Alfuzosin-d₃ is deuterium labeled Alfuzosin.

HY-B0154S

Fluticasone propionate-d₃
Fluticasone propionate-d₃ is the deuterium labeled Fluticasone propionate. Fluticasone propionate, a potent topical anti-inflammatory corticosteroid, is a selective glucocorticoid receptor agonist, with an absolute affinity (KD) of 0.5 nM. Fluticasone propionate shows little or no activity at other steroid receptors. Anti-viral activity.

HY-W654000

Cyclic GMP-¹³C,¹⁵N₂		98.81%
Cyclic GMP-¹³C,¹⁵N₂ is ¹³C and ¹⁵N labeled Cyclic GMP (HY-113469). Cyclic GMP (cGMP), an important second messenger, is a major intracellular mediator of extracellular signals such as nitric oxide (NO) and natriuretic peptides (NPs). Effects of Cyclic GMP occur through three main groups of cellular targets: cGMP-dependent protein kinases (PKGs), cGMP-gated cation channels, and PDEs. Cyclic GMP can inhibit both platelet adhesion and aggregation. cGAMP (Cyclic-GMP-AMP) (HY-12512), a conjugate of Cyclic GMP and AMP, can induce IRF3 phosphorylation and nuclear translocation, enhancing antiviral immune responses.

HY-101404S

DL-Homocysteine thiolactone-d₄ hydrochloride		99.83%
DL-Homocysteine thiolactone-d4 hydrochloride is the deuterium labeled DL-Homocysteine thiolactone (hydrochloride). DL-Homocysteine thiolactone hydrochloride is a cyclic amino acid derivative that exhibits root-growth inhibitory activity.

HY-32149S

1-Bromo-3-iodobenzene-d₄
1-Bromo-3-iodobenzene-d₄ is the deuterium labeled 1-Bromo-3-iodobenzene (HY-32149). 1-Bromo-3-iodobenzene is a biochemical reagent and an important organic synthetic intermediate. 1-Bromo-3-iodobenzene can be used for the synthesis of other active compounds.

HY-158087S

N-(1-Oxopentadecyl)glycine-d₂
N-(1-Oxopentadecyl)glycine-d₂ is the deuterated labeled N-(1-Oxopentadecyl)glycine.

HY-W141928S

N-Isobutyryl-glycine-d₇		99%
N-Isobutyryl-glycine-d₇ is the deuterium labeled N-Isobutyryl-glycine.

HY-W777283

Idebenone-¹³C,d₃		99.62%
Idebenone-¹³C,d₃ is the deuterium labeled and ¹³C-labeled Idebenone (HY-N0303). Idebenone, a well-appreciated mitochondrial protectant, exhibits protective efficacy against neurotoxicity and can be used for the research of Alzheimer's disease, Huntington's disease. Idebenone (oxidised form) has a dose-dependent inhibitory effect on the enzymatic metabolism of arachidonic acid in astroglial homogenates (IC₅₀=16.65 μM). Idebenone, a coenzyme Q10 analog and an antioxidant, induces apoptotic cell death in the human dopaminergic neuroblastoma SHSY-5Y cells. Idebenone quickly crosses the blood-brain barrier.

HY-B0010AS

Formoterol-d₃		99.60%
Formoterol-d₃ is deuterium labeled Arformoterol. Arformoterol ((R,R)-Formoterol), the (R,R)-enantiomer of Formoterol, is a long-acting β2-adrenergic receptor (β2-AR) agonist, with a Kd of 2.9 nM. Arformoterol can be used for the research of chronic obstructive pulmonary disease (COPD).

HY-W015824S1

DL-Aspartic acid-¹³C,¹⁵N
DL-Aspartic acid-¹³C,¹⁵N is the ¹³C, and ¹⁵N-labeled DL-Aspartic acid.

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