2. Signaling Pathways
  3. Epigenetics
  4. Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA)

Small Interfering RNA (siRNA) is a small exogenous double-stranded RNA (dsRNA) (20-25 nucleotides), which triggers the RNA interference (RNAi) pathway. The short dsRNA unwinds and the sense strand is degraded. Antisense strand forms RNA induced silencing complex (RISC) with various protein components. The antisense strand retained in RISC is specifically complementary to the target gene mRNA. Meanwhile, RISC has nuclease activity, which can cut and degrade the target gene mRNA, and inhibit the expression of target gene. Incomplete complementarity results in mRNA translation inhibition.

Small Interfering RNA (siRNA) Related Products (29582):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-RS07231
    Keap1 Mouse Pre-designed siRNA Set A
    		Pre-designed Set

    Keap1 Mouse Pre-designed siRNA Set A contains three designed siRNAs for Keap1 gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
    Keap1 Mouse Pre-designed siRNA Set A
  • HY-153484A
    Bevasiranib sodium
    Bevasiranib sodium is a siRNA designed to silence the genes that produce vascular endothelial growth factor (VEGF). It is widely accepted that vascular endothelial growth factor (VEGF) is a key component in the pathogenesis of choroidal neo-vascularization (CNV), which is a precursor to wet age-related macular degeneration (wet AMD).
    Bevasiranib sodium
  • HY-RS12110
    ROBO1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ROBO1 Human Pre-designed siRNA Set A contains three designed siRNAs for ROBO1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ROBO1 Human Pre-designed siRNA Set A
  • HY-RS09491
    NPM2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    NPM2 Human Pre-designed siRNA Set A contains three designed siRNAs for NPM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    NPM2 Human Pre-designed siRNA Set A
  • HY-RS15003
    TREM2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    TREM2 Human Pre-designed siRNA Set A contains three designed siRNAs for TREM2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    TREM2 Human Pre-designed siRNA Set A
  • HY-RS06994
    ITPRID2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ITPRID2 Human Pre-designed siRNA Set A contains three designed siRNAs for ITPRID2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ITPRID2 Human Pre-designed siRNA Set A
  • HY-RS01745
    C4A Human Pre-designed siRNA Set A
    		Pre-designed Set

    C4A Human Pre-designed siRNA Set A contains three designed siRNAs for C4A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    C4A Human Pre-designed siRNA Set A
  • HY-RS13796
    SRSF5 Human Pre-designed siRNA Set A
    		Pre-designed Set

    SRSF5 Human Pre-designed siRNA Set A contains three designed siRNAs for SRSF5 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    SRSF5 Human Pre-designed siRNA Set A
  • HY-RS03331
    CTSE Human Pre-designed siRNA Set A
    		Pre-designed Set

    CTSE Human Pre-designed siRNA Set A contains three designed siRNAs for CTSE gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CTSE Human Pre-designed siRNA Set A
  • HY-RS00815
    APEX1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    APEX1 Human Pre-designed siRNA Set A contains three designed siRNAs for APEX1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    APEX1 Human Pre-designed siRNA Set A
  • HY-RS08418
    MGST3 Human Pre-designed siRNA Set A
    		Pre-designed Set

    MGST3 Human Pre-designed siRNA Set A contains three designed siRNAs for MGST3 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    MGST3 Human Pre-designed siRNA Set A
  • HY-RS09078
    NCF2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    NCF2 Human Pre-designed siRNA Set A contains three designed siRNAs for NCF2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    NCF2 Human Pre-designed siRNA Set A
  • HY-RS04241
    EIF2A Human Pre-designed siRNA Set A
    		Pre-designed Set

    EIF2A Human Pre-designed siRNA Set A contains three designed siRNAs for EIF2A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EIF2A Human Pre-designed siRNA Set A
  • HY-RS04436
    EPHB4 Human Pre-designed siRNA Set A
    		Pre-designed Set

    EPHB4 Human Pre-designed siRNA Set A contains three designed siRNAs for EPHB4 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    EPHB4 Human Pre-designed siRNA Set A
  • HY-RS05153
    FUT2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    FUT2 Human Pre-designed siRNA Set A contains three designed siRNAs for FUT2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    FUT2 Human Pre-designed siRNA Set A
  • HY-RS02726
    CISH Human Pre-designed siRNA Set A
    		Pre-designed Set

    CISH Human Pre-designed siRNA Set A contains three designed siRNAs for CISH gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    CISH Human Pre-designed siRNA Set A
  • HY-RS11421
    PTPN2 Human Pre-designed siRNA Set A
    		Pre-designed Set

    PTPN2 Human Pre-designed siRNA Set A contains three designed siRNAs for PTPN2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    PTPN2 Human Pre-designed siRNA Set A
  • HY-RS11591
    RAC1 Human Pre-designed siRNA Set A
    		Pre-designed Set

    RAC1 Human Pre-designed siRNA Set A contains three designed siRNAs for RAC1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    RAC1 Human Pre-designed siRNA Set A
  • HY-RS06813
    INHBA Human Pre-designed siRNA Set A
    		Pre-designed Set

    INHBA Human Pre-designed siRNA Set A contains three designed siRNAs for INHBA gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    INHBA Human Pre-designed siRNA Set A
  • HY-RS06970
    ITGB6 Human Pre-designed siRNA Set A
    		Pre-designed Set

    ITGB6 Human Pre-designed siRNA Set A contains three designed siRNAs for ITGB6 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
    ITGB6 Human Pre-designed siRNA Set A