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Bevasiranib sodium

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Bevasiranib sodium is a siRNA that targets and silences VEGF-A. Bevasiranib sodium activates the RNA-induced silencing complex to degrade VEGF-A mRNA, mediates TLR3-related inhibition of choroidal neovascularization, and triggers RNA interference-mediated gene silencing through endogenous eukaryotic RNAi mechanisms. After intravitreal injection, Bevasiranib sodium distributes to various ocular tissues and resists degradation by intraocular nucleases, reducing choroidal neovascularization area and alleviating vascular leakage. Bevasiranib sodium can be used in research related to macular degeneration.

For research use only. We do not sell to patients.

  • Purity : 97.99%
  • CAS No.: 849758-52-7
  • Molecular Weight:13345.2 (free acid)
  • Storage:

    -20°C, sealed storage, away from moisture

    * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

  • Bevasiranib sodium Chemical Structure
    Bevasiranib sodium Chemical Structure
CAS No.: 849758-52-7
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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All VEGFR Isoforms

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  • Bevasiranib sodium Chemical Structure
    Bevasiranib sodium Chemical Structure RNA, (A-C-C-U-C-A-C-C-A-A-G-G-C-C-A-G-C-A-C-dT-dT), eicosasodium salt, complex with RNA (G-U-G-C-U-G-G-C-C-U-U-G-G-U-G-A-G-G-U-dT-dT) eicosasodium salt (1:1)
    1/16
  • RNA, (A-C-C-U-C-A-C-C-A-A-G-G-C-C-A-G-C-A-C-dT-dT), eicosasodium salt, complex with RNA (G-U-G-C-U-G-G-C-C-U-U-G-G-U-G-A-G-G-U-dT-dT) eicosasodium salt (1:1)