Adenine-¹³C₅,¹⁵N₅  (Synonyms: 6-Aminopurine-¹³C₅,¹⁵N₅; Vitamin B4-¹³C₅,¹⁵N₅)

Adenine-¹³C₅,15C5 (6-Aminopurine-¹³C₅,15C5; Vitamin B4-¹³C₅,15C5) is ¹³C-labeled Adenine (HY-B0152). Adenine (6-Aminopurine), a purine, is one of the four nucleobases in the nucleic acid of DNA. Adenine acts as a chemical component of DNA and RNA. Adenine also plays an important role in biochemistry involved in cellular respiration, the form of both ATP and the cofactors (NAD and FAD), and protein synthesis.

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

145.06

¹³C₅H₅¹⁵N₅

[15NH2][13C]1=[15N][13CH]=[15N][13C]2=[13C]1[15N]=[13CH][15NH]2

Room temperature in continental US; may vary elsewhere.

Please store the product under the recommended conditions in the Certificate of Analysis.

• [1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  [Content Brief]

  [2]. ORO J, et al. Synthesis of purines under possible primitive earth conditions. I. Adenine from hydrogen cyanide. Arch Biochem Biophys. 1961 Aug;94:217-27.  [Content Brief]

  [3]. Griffiths AJF, et al. An Introduction to Genetic Analysis. 7th edition. New York: W. H. Freeman; 2000. Structure of DNA.

  [4]. Reader V. The assay of vitamin B(4). Biochem J. 1930;24(6):1827-31.  [Content Brief]