Sarcomeric alpha Actinin Antibody (YA5771)

Cat. No.: HY-P86079: Data Sheet COA
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Sarcomeric alpha Actinin Antibody (YA5771) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.

For research use only. We do not sell to patients.

Size	Stock	Quantity
20 μL	In-stock	Estimated Time of Arrival: December 31
50 μL	In-stock	Estimated Time of Arrival: December 31
100 μL	In-stock	Estimated Time of Arrival: December 31
250 μL	Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

Sarcomeric alpha Actinin Antibody (YA5771) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Sarcomeric alpha Actinin.

Host

Rabbit

Clonality

Monoclonal

Molecular Weight

Predicted band size: 104 kDa;

Observed band size: 104 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

P35609

Gene ID

88 [NCBI]

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1:1000
WB WB: Western Blot	1:500-1:2000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-1:20000
IP IP: Immunoprecipitation	1:50-1:200

Purity	Protein A	Conjugation	Non-conjugated
Modification	Unmodified	Isotype	IgG/Kappa

Appearance

Liquid

Formulation

Supplied in PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. This is a bundling protein

Subcellular Localization：Cytoplasm, myofibril, sarcomere, Z line

Expression：
Tissue_specificity:It is expressed in both skeletal muscle and cardiac muscle.

Isoforms & Post-Translational Modification：P35609 has 2 isomers: P35609-1: 103854 Da (predicted); P35609-2: 103920 Da (predicted).
Ubiquitinated by FBXL22, leading to proteasomal degradation

Subunit：Homodimer; antiparallel. Also forms heterodimers with ACTN3. Interacts with ADAM12, MYOZ1, MYOZ2 and MYOZ3. Interacts via its C-terminal region with the LDB3 PDZ domain. Interacts with XIRP2. Interacts with DST isoform 1 (via N-terminus). Interacts with PARVB. Interacts with SYNPO2

Synonyms

ACTN2; Alpha-actinin-2; Alpha-actinin skeletal muscle isoform 2; F-actin cross-linking protein

Documentation

Select Batch:

Data Sheet (235 KB) SDS (251 KB)

COA (205 KB)

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/u-937-cell.html [Content Brief]