Phospho-p70 S6 kinase β (Ser371) Antibody (YA7520)

Cat. No.: HY-P87835: Data Sheet User Guide for Antibodies
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Phospho-p70 S6 kinase β (Ser371) Antibody (YA7520) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-p70 S6 kinase β (Ser371).

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation
References

Description

Phospho-p70 S6 kinase β (Ser371) Antibody (YA7520) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-p70 S6 kinase β (Ser371).

Host

Rabbit

Clonality

Monoclonal,Recombinant

Molecular Weight

Predicted band size: 53 kDa;

Observed band size: 60 kDa

Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9UBS0

Immunogen

The exact sequence is proprietary to MCE.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-1:2000
WB WB: Western Blot	1:2000-1:10000
ICC/IF ICC/IF: Immunocytochemistry/Immunofluorescence	1:200-1:1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:5000-1:20000

Sensitivity	Endogenous	Purity	Protein A affinity purified
Conjugation	Non-conjugated	Modification	Phosphorylated
Isotype	IgG, Kappa

Appearance

Liquid

Formulation

Supplied in PBS (pH7.4) containing 50% glycerol, 0.05% Proclin 300, 0.05%BSA

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Phosphorylates specifically ribosomal protein S6 (PubMed:29750193). Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193)

Subcellular Localization：Cytoplasm,Nucleus

Isoforms & Post-Translational Modification：Q9UBS0 has two isomers: Q9UBS0-1: 53455 Da (predicted); Q9UBS0-2: 16868 Da (predicted).
Phosphorylated and activated by MTOR

Documentation

User Guide for Antibodies (1077 KB)

References

[1]. /biology-dictionary/mda-mb-231-cell.html [Content Brief]