1. Biology Dictionary
  2. Acute febrile neutrophilic dermatosis

Acute febrile neutrophilic dermatosis

Definition:

Acute febrile neutrophilic dermatosis (AFND), also referred to as pyrin-associated autoinflammatory disease (PAAND), is an autosomal dominant autoinflammatory disorder characterized by fever and arthritis. Pyrin encoded by MEFV gene is a protein involved as a suppressor of inflammasome and mutations in the MEFV gene have been linked to AFND.

Biomedical Dictionary

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