BTB/POZ domain-containing protein KCTD5

Definition:

Its interaction with CUL3 suggests that it may act as a substrate adapter in some E3 ligase complex. Does not affect the function of Kv channel Kv2.1/KCNB1, Kv1.2/KCNA2, Kv4.2/KCND2 and Kv3.4/KCNC4.

References:

[1]. Yolanda Bayón, et al. KCTD5, a putative substrate adaptor for cullin3 ubiquitin ligases. FEBS J. 2008 Aug;275(15):3900-10. [Content Brief]

[2]. Irina S Dementieva, et al. Pentameric assembly of potassium channel tetramerization domain-containing protein 5. J Mol Biol. 2009 Mar 20;387(1):175-91. [Content Brief]

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