Butyrophilin subfamily 3 member A2

Definition:

Plays a role in T-cell responses in the adaptive immune response. Inhibits the release of IFNG from activated T-cells.

References:

[1]. Nassima Messal, et al. Differential role for CD277 as a co-regulator of the immune signal in T and NK cells. Eur J Immunol. 2011 Dec;41(12):3443-54. [Content Brief]

[2]. Christelle Harly, et al. Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset. Blood. 2012 Sep 13;120(11):2269-79. [Content Brief]

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