C-type lectin domain family 12 member A

Definition:

Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases.

References:

[1]. Chang-Hung Chen, et al. Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. Blood. 2006 Feb 15;107(4):1459-67. [Content Brief]

[2]. Andrew S J Marshall, et al. Identification and characterization of a novel human myeloid inhibitory C-type lectin-like receptor (MICL) that is predominantly expressed on granulocytes and monocytes. J Biol Chem. 2004 Apr 9;279(15):14792-802. [Content Brief]

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