Centrosomal protein of 85 kDa

Definition:

Acts as a negative regulator of NEK2 to maintain the centrosome integrity in interphase. Suppresses centrosome disjunction by inhibiting NEK2 kinase activity.

References:

[1]. Canhe Chen, et al. Characterization of Cep85 - a new antagonist of Nek2A that is involved in the regulation of centrosome disjunction. J Cell Sci. 2015 Sep 1;128(17):3290-303. [Content Brief]

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