Hemorrhagic fever with renal syndrome

Definition:

Hemorrhagic fever with renal syndrome (HFRS) is a group of diseases caused by hantaviruses which are members of family Bunyaviridae. Rodents and Soricomorpha species are natural reservoirs of these viruses, and humans acquire infection by inhaling the excreta of infected animals. HFRS is characterized by renal failure, hemorrhages, and shock. The serotype Puumala virus also causes nephropathia epidemica, a milder variant of HFRS.

References:

[1]. Hiroaki Kariwa, et al. Isolation and characterization of hantaviruses in Far East Russia and etiology of hemorrhagic fever with renal syndrome in the region. Am J Trop Med Hyg. 2012 Mar;86(3):545-53. [Content Brief]

[2]. Martin Zeier, et al. New ecological aspects of hantavirus infection: a change of a paradigm and a challenge of prevention--a review. Virus Genes. 2005 Mar;30(2):157-80. [Content Brief]

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