1. Biology Dictionary
  2. Heterochromatin protein 1-binding protein 3

Heterochromatin protein 1-binding protein 3

Definition:

Component of heterochromatin that maintains heterochromatin integrity during G1/S progression and regulates the duration of G1 phase to critically influence cell proliferative capacity. Mediates chromatin condensation during hypoxia, leading to increased tumor cell viability, radio-resistance, chemo-resistance and self-renewal.

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