Intraflagellar transport protein 52 homolog

Definition:

Involved in ciliogenesis as part of a complex involved in intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Required for the anterograde transport of IFT88.

References:

[1]. Wenjuan Zhang, et al. IFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome. Hum Mol Genet. 2016 Sep 15;25(18):4012-4020. [Content Brief]

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