2. Biology Dictionary
  3. Isolated congenital nail clubbing

Isolated congenital nail clubbing

Definition:

Isolated congenital nail clubbing (ICNC) is a rare autosomal recessive disorder characterised by enlargement of the terminal segments of fingers and toes with thickened nails due to proliferation of the connective tissues and abnormal function of the nail matrix. It has been reported that mutation in the HPGD gene underlies ICNC.

Biomedical Dictionary

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