1. Biology Dictionary
  2. Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2

Definition:

Seems to act as a scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins (By similarity). Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth (By similarity). May play a role in regulating activin-mediated signaling in neuronal cells (By similarity). Enhances the ability of PTEN to suppress AKT1 activation. Plays a role in receptor-mediated clathrin-dependent endocytosis which is required for ciliogenesis (By similarity).

Biomedical Dictionary

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