mRNA turnover protein 4 homolog

Definition:

Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes.

References:

[1]. Barbara Michalec, et al. Subcellular localization of ribosomal P0-like protein MRT4 is determined by its N-terminal domain. Int J Biochem Cell Biol. 2010 May;42(5):736-48. [Content Brief]

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