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Results for "

n2a-cell

" in MedChemExpress (MCE) Product Catalog:

4

Inhibitors & Agonists

1

Natural
Products

Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-B2134
    Casanthranol

    		Others Metabolic Disease
    Casanthranol is a concentrated mixture of anthranol glycosides from cascara sagrada (dried bark of Rhamnus p.). Casanthranol can be used as a laxative in constipation and various medical conditions, stimulant laxative. Casanthranol encourages bowel movements by acting on the intestinal wall to increase muscle contractions. Casanthranol is protective in a PFF-induced toxicity model (EC50 = 34.2 μM) of N2a cells [2].
    Casanthranol
  • HY-169025
    ADH-353

    		Amyloid-β Neurological Disease
    ADH-353 can inhibit Aβ fibrillation and reduce Aβ-induced cytotoxicity in SH-SY5Y and N2a cells. ADH-353 can be used in Alzheimer's disease-related research .
    ADH-353
  • HY-170931
    AMPK activator 16

    		AMPK Acetyl-CoA Carboxylase Neurological Disease Metabolic Disease
    AMPK activator 16 (compound 6) is a AMP-activated protein kinase (AMPK) inhibitor. AMPK activator 16 shows the most efficient interactions with the key residues of AMPK and demonstrates significant activation of AMPK. AMPK activator 16 increases the expression of phosphorylated AMPK (p-AMPK) and its downstream signaling proteins, such as phosphorylated ACC (Acetyl-CoA Carboxylase) (p-ACC) and phosphorylated raptor (p-raptor), in N2a cells .
    AMPK activator 16
  • HY-169907
    Anticancer agent 258

    		Nuclear Hormone Receptor 4A/NR4A Neurological Disease Metabolic Disease Cancer
    Anticancer agent 258 is an imidazo [1,2-B][1,2,4] triazol derivative. Anticancer agent 258 regulates the activity of nuclear receptors. Anticancer agent 258 has an EC50 of 63 nM against Nurr in N2A cells. Anticancer agent 258 has IC50 of 0.1 pM for Nur77 in HEK293 cells. Anticancer agent 258 can be used in the study of cancer, metabolic diseases and neurological disorders .
    Anticancer agent 258

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