Receptor-binding cancer antigen expressed on SiSo cells

Definition:

May participate in suppression of cell proliferation and induces apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases.

References:

[1]. Satoshi Oizumi, et al. RCAS1 expression: a potential prognostic marker for adenocarcinomas of the lung. Oncology. 2002;62(4):333-9. [Content Brief]

[2]. Joel Rousseau, et al. RCAS1 is associated with ductal breast cancer progression. Biochem Biophys Res Commun. 2002 May 24;293(5):1544-9. [Content Brief]

[3]. Arne Engelsberg, et al. The Golgi protein RCAS1 controls cell surface expression of tumor-associated O-linked glycan antigens. J Biol Chem. 2003 Jun 20;278(25):22998-3007. [Content Brief]

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