rRNA N6-adenosine-methyltransferase ZCCHC4

Definition:

rRNA N6-methyltransferase that specifically methylates the adenine in position 4220 of 28S rRNA. N6-methylation of adenine(4220) in 28S rRNA is required for translation.

References:

[1]. Wendan Ren, et al. Structure and regulation of ZCCHC4 in m6A-methylation of 28S rRNA. Nat Commun. 2019 Nov 6;10(1):5042. [Content Brief]

[2]. Honghui Ma, et al. N6-Methyladenosine methyltransferase ZCCHC4 mediates ribosomal RNA methylation. Nat Chem Biol. 2019 Jan;15(1):88-94. [Content Brief]

[3]. Nhan van Tran, et al. The human 18S rRNA m6A methyltransferase METTL5 is stabilized by TRMT112. Nucleic Acids Res. 2019 Sep 5;47(15):7719-7733. [Content Brief]

[4]. Rita Pinto, et al. The human methyltransferase ZCCHC4 catalyses N6-methyladenosine modification of 28S ribosomal RNA. Nucleic Acids Res. 2020 Jan 24;48(2):830-846. [Content Brief]

Biomedical Dictionary

The Biomedical Dictionary is a comprehensive and professional collection of biological academic terms and subject datas. All explanations are supported by authoritative books or high impact factor literatures, and you can acquire accurate explanations of the biomedical terms you want to know.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Name
Email *

	Sorry, but the email address you supplied was invalid.